TABLE 1.
Variable | All | AD | IgE-FA | Asthma | AR | EoE | |||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
n | % | n | % | P | n | % | P | n | % | P | n | % | P | n | % | P | |
Sexa | |||||||||||||||||
Male | 111 577 | 51.1 | 11 983 | 53.4 | — | 5100 | 58.6 | — | 26 015 | 59.3 | — | 24 002 | 55.8 | — | 166 | 70.9 | — |
Female | 106 907 | 48.9 | 10 454 | 46.6 | <.0001 | 3606 | 41.4 | <.0001 | 17 837 | 40.7 | <.0001 | 19 031 | 44.2 | <.0001 | 68 | 29.1 | <.0001 |
Raceb | |||||||||||||||||
White | 103 942 | 47.6 | 6778 | 30.2 | — | 4234 | 48.6 | — | 17 141 | 39.1 | — | 18 725 | 43.5 | — | 141 | 60.3 | — |
Black | 69 796 | 31.9 | 11 489 | 51.3 | <.0001 | 2861 | 32.9 | <.01 | 19 477 | 44.4 | <.0001 | 18 200 | 42.3 | <.0001 | 54 | 23.1 | <.01 |
Asian or Pacific Islander | 6210 | 2.8 | 908 | 4.0 | <.0001 | 513 | 5.9 | <.0001 | 1098 | 2.5 | NS | 1092 | 2.5 | NS | 13 | 5.5 | NS |
Unknown | 14 393 | 6.6 | 1439 | 6.4 | <.0001 | 577 | 6.6 | <.0001 | 2761 | 6.3 | NS | 2457 | 5.7 | <.0001 | 14 | 6.0 | <.05 |
Other | 24 144 | 11.1 | 1823 | 8.1 | <.0001 | 521 | 6.0 | NS | 3376 | 7.7 | NS | 2560 | 6.0 | <.0001 | 12 | 5.1 | NS |
Ethnicity | |||||||||||||||||
Non-Hispanic | 166 521 | 76.2 | 18 074 | 80.5 | — | 7657 | 88.0 | — | 35 125 | 80.1 | — | 36 463 | 84.7 | — | 202 | 86.3 | — |
Hispanic | 22 195 | 10.2 | 2102 | 9.4 | <.0001 | 516 | 5.9 | <.0001 | 4497 | 10.3 | <.0001 | 3871 | 9.0 | <.0001 | 24 | 10.3 | NS |
Other | 29 769 | 13.6 | 2261 | 10.1 | <.0001 | 533 | 6.1 | <.0001 | 4231 | 9.6 | <.0001 | 2700 | 6.3 | <.0001 | 8 | 3.4 | <.01 |
Birth year | |||||||||||||||||
Pre-2000 | 3337 | 1.5 | 187 | 0.8 | — | 36 | 0.4 | — | 676 | 1.5 | — | 505 | 1.2 | — | 2 | 0.9 | — |
2000–2004 | 41 898 | 19.2 | 5226 | 23.3 | <.0001 | 1294 | 14.9 | <.05 | 9877 | 22.5 | <.0001 | 9417 | 21.9 | NS | 30 | 12.8 | NS |
2005–2009 | 94 489 | 43.3 | 10 562 | 47.1 | <.0001 | 4139 | 47.5 | <.01 | 20 074 | 45.8 | <.0001 | 21 023 | 48.8 | <.0001 | 127 | 54.3 | NS |
2010–2014 | 76 919 | 35.2 | 6286 | 28.0 | NS | 3156 | 36.3 | NS | 12 988 | 29.6 | <.0001 | 11 915 | 27.7 | <.0001 | 74 | 31.6 | NS |
2015 or later | 1842 | 0.8 | 176 | 0.8 | NS | 81 | 0.9 | NS | 238 | 0.6 | <.0001 | 174 | 0.4 | <.0001 | 1 | 0.4 | NS |
Total | 218 485 | 100.0 | 22 437 | 100.0 | — | 8706 | 100.0 | — | 43 853 | 100.0 | — | 43 034 | 100.0 | — | 234 | 100.0 | — |
Race was not available for 20 343 (9.3% of total) subjects. P value presented in boldface if <.05. AD, atopic dermatitis; AR, allergic rhinitis; EoE, eosinophilic esophagitis; IgE-FA, immunoglobulin E–mediated food allergy; NS, not significant.
In the full cohort and asthma and AR subcohorts, sex was unknown for 1 subject.
The race category “Unknown” represents subjects with self-identified unknown race, whereas “Other” comprises all other entries including “American Indian or Alaska Native,” “Mixed racial group,” and “Race not available.”