Abstract
A double-blind stratified trial was carried out on 85 patients to assess the efficacy of topical therapy with 1% chlortetracycline eye ointment in comparison with 1% rifampicin eye ointment in the treatment of chlamydial ocular infection of sexually transmitted origin (paratrachoma). Patients included were selected on the basis of positive culture for Chlamydia trachomatis. A 6-week course of treatment with chlortetracycline or rifampicin 3 times daily gave a clinical cure rate of 80% and 75% and a microbiological cure rate of 93% and 86% respectively. In patients who were not cured the intensity of inflammatory responses was considerably reduced.
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Selected References
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- Darougar S., Jones B. R. Conjunctival swabbing for the isolation of TRIC agent (Chlamydia). Br J Ophthalmol. 1971 Sep;55(9):585–590. doi: 10.1136/bjo.55.9.585. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Darougar S., Jones B. R., Viswalingam N., Allami J., Minassian D., Farahmandian M. A., Houshmand A. Topical therapy of hyperendemic trachoma with rifampicin, oxytetracycline, or spiramycin eye ointments. Br J Ophthalmol. 1980 Jan;64(1):37–42. doi: 10.1136/bjo.64.1.37. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Darougar S., Viswalingam M., Treharne J. D., Kinnison J. R., Jones B. R. Treatment of TRIC infection of the eye with rifampicin or chloramphenicol. Br J Ophthalmol. 1977 Apr;61(4):255–259. doi: 10.1136/bjo.61.4.255. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Dawson C. R., Jones B. R., Darougar S. Blinding and non-blinding trachoma: assessment of intensity of upper tarsal inflammatory disease and disabling lesions. Bull World Health Organ. 1975;52(3):279–282. [PMC free article] [PubMed] [Google Scholar]