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. 1982 Jul;66(7):422–431. doi: 10.1136/bjo.66.7.422

Tapetoretinal degeneration in the cerebro-hepato-renal (Zellweger's) syndrome.

A Garner, A R Fielder, R Primavesi, A Stevens
PMCID: PMC1039816  PMID: 7093180

Abstract

Electrophysiological and histopathological study of a baby suffering from Zellweger's syndrome and presenting progressive retinal dysfunction showed this to be related to degenerative changes in the photoreceptor cells and pigment epithelium and to defective myelination of the optic nerve. Disturbances of bile acid and lysine metabolism were also demonstrated, lending support to the concept that Zellweger's syndrome is attributable to a widespread inadequacy of intracellular oxidative function.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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