Abstract
Tear and serum IgG, IgA, and IgM levels were measured in 35 healthy subjects and 31 patients with acute conjunctivitis due to adenovirus 2, 7, and 8 infections. Serum IgG and IgM levels were found to be significantly low and there was no change in the serum IgA level. There was a significant rise in the tear IgG level. A progressive decline in the serum immunoglobulin level with the severity of the disease was observed. The changes in the immunoglobulin levels in serum and tears showed a tendency to reach normal levels with clinical improvement.
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- Barnett E. V. Quantitation of immunoglobulins and L-chains by complement fixation tests. J Immunol. 1968 May;100(5):1093–1100. [PubMed] [Google Scholar]
- Bluestone R., Easty D. L., Goldberg L. S., Jones B. R., Pettit T. H. Lacrimal immunoglobulins and complement quantified by counter-immunoelectrophoresis. Br J Ophthalmol. 1975 May;59(5):279–281. doi: 10.1136/bjo.59.5.279. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Chandler J. W., Leder R., Kaufman H. E., Caldwell J. R. Quantitative determinations of complement components and immunoglobulins in tears and aqueous humor. Invest Ophthalmol. 1974 Feb;13(2):151–153. [PubMed] [Google Scholar]
- Diallo J., Castets M., Bassabi S., Marty A propos d'une conjonctivite hémorragique épidémique. Bull Soc Med Afr Noire Lang Fr. 1971;16(1):73–75. [PubMed] [Google Scholar]
- GRAYSTON J. T., YANG Y. F., JOHNSTON P. B., KO L. S. EPIDEMIC KERATOCONJUNCTIVITIS ON TAIWAN: ETIOLOGICAL AND CLINICAL STUDIES. Am J Trop Med Hyg. 1964 May;13:492–498. doi: 10.4269/ajtmh.1964.13.492. [DOI] [PubMed] [Google Scholar]
- Gaudin O. G., Omari M., Bouayed R. Isolement de l'Entérovirus 70 au cours d'une épidémie de conjonctivite aiguë hémorragique en Algérie en 1973. Arch Inst Pasteur Alger. 1977;52:119–128. [PubMed] [Google Scholar]
- Jones B. R. Epidemic haemorrhagic conjunctivitis in London 1971: a conjunctival picornavirus infection. Trans Ophthalmol Soc U K. 1972;92:625–627. [PubMed] [Google Scholar]
- Josephson A. S., Weiner R. S. Studies of the proteins of lacrimal secretions. J Immunol. 1968 May;100(5):1080–1081. [PubMed] [Google Scholar]
- Kelkar S. S., Warawdekar W., Dhunjibhoy K. Serum immunoglobulins G, M and A in acute viral hepatitis. Indian J Med Res. 1981 May;73:673–677. [PubMed] [Google Scholar]
- Knopf H. L., Bertran D. M., Kapikian A. Z. Demonstration and characterization of antibody in tears following intranasal vaccination with inactivated type 13 rhinovirus: a preliminary report. Invest Ophthalmol. 1970 Oct;9(10):727–734. [PubMed] [Google Scholar]
- Little J. M., Centifanto Y. M., Kaufman H. E. Immunoglobulins in human tears. Am J Ophthalmol. 1969 Nov;68(5):898–905. doi: 10.1016/0002-9394(69)94587-5. [DOI] [PubMed] [Google Scholar]
- McClellan B. H., Whitney C. R., Newman L. P., Allansmith M. R. Immunoglobulins in tears. Am J Ophthalmol. 1973 Jul;76(1):89–101. doi: 10.1016/0002-9394(73)90015-9. [DOI] [PubMed] [Google Scholar]
- Parrott W. F. An epidemic called Apollo. An outbreak of conjuctivitis in Nigeria. Practitioner. 1971 Feb;206(232):253–255. [PubMed] [Google Scholar]
- Sen D. K., Sarin G. S. Immunoglobulin concentrations in human tears in ocular diseases. Br J Ophthalmol. 1979 May;63(5):297–300. doi: 10.1136/bjo.63.5.297. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Sen D. K., Sarin G. S., Mani K., Saha K. Immunoglobulins in tears of normal Indian people. Br J Ophthalmol. 1976 Apr;60(4):302–304. doi: 10.1136/bjo.60.4.302. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Tan D. S., Yin-Murphy M., Kandiah S. An outbreak of acute conjunctivitis caused by coxsackievirus A24 in Kuala-Lumpur, Malaysia, 1978. Southeast Asian J Trop Med Public Health. 1980 Mar;11(1):24–27. [PubMed] [Google Scholar]
- Tullo A. B., Higgins P. G. An outbreak of adenovirus keratoconjunctivitis in bristol. Br J Ophthalmol. 1979 Sep;63(9):621–626. doi: 10.1136/bjo.63.9.621. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Yokoyama M. M., Matsui Y., Yamashiroya H. M., O'Donnell M. J., Tseng C. H., Snyder D. A., Tessler H. H., Crispen R. G., Zimjewski C. M. Humoral and cellular immunity studies in patients with Vogt-Koyanagi-Harada syndrome and pars planitis. Invest Ophthalmol Vis Sci. 1981 Mar;20(3):364–370. [PubMed] [Google Scholar]