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. 1983 Jun;67(6):385–388. doi: 10.1136/bjo.67.6.385

Effect of the method of enucleation on the prognosis of choroidal melanoma.

C Migdal
PMCID: PMC1040070  PMID: 6849859

Abstract

The prognosis following treatment of uveal melanomata depends not only on factors such as cell type and degree of mitotic activity, size and location of the tumour, and the age of the patient, but also on the method of enucleation, as surgical manipulation of the neoplasm may potentiate the shedding of malignant cells into the blood stream. One hundred and thirty-one patients treated by different methods of enucleation were reviewed and the mortality patterns assessed. The numbers of deaths over the first 5 years differed significantly between the different groups. A specific method of enucleation used for tumour-containing eyes is described and its importance emphasised.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. Benjamin B., Cumings J. N., Goldsmith A. J., Sorsby A. PROGNOSIS IN UVEAL MELANOMA. Br J Ophthalmol. 1948 Oct;32(10):729–747. [PMC free article] [PubMed] [Google Scholar]
  2. COLE W. H., ROBERTS S., WATNE A., McDONALD G., McGREW E. The dissemination of cancer cells. Bull N Y Acad Med. 1958 Mar;34(3):163–183. [PMC free article] [PubMed] [Google Scholar]
  3. Davidorf F. H. Treatment of malignant melanoma. Arch Ophthalmol. 1979 May;97(5):975–976. doi: 10.1001/archopht.1979.01020010513034. [DOI] [PubMed] [Google Scholar]
  4. Federman J. L., Felberg N. T., Shields J. A. Effect of local treatment on antibody levels in malignant melanoma of the choroid. Trans Ophthalmol Soc U K. 1977 Sep;97(3):436–439. [PubMed] [Google Scholar]
  5. Horodeński J. Badania nad obecnościa wolnych komórek czerniaka złośliwego jagodówki we krwi obwodowej. Klin Oczna. 1969;39(3):407–412. [PubMed] [Google Scholar]
  6. Manschot W. A., van Peperzeel H. A. Choroidal melanoma. Enucleation or observation? A new approach. Arch Ophthalmol. 1980 Jan;98(1):71–77. doi: 10.1001/archopht.1980.01020030073002. [DOI] [PubMed] [Google Scholar]
  7. Packard R. B. Pattern of mortality in choroidal malignant melanoma. Br J Ophthalmol. 1980 Aug;64(8):565–575. doi: 10.1136/bjo.64.8.565. [DOI] [PMC free article] [PubMed] [Google Scholar]
  8. Seigel D., Myers M., Ferris F., 3rd, Steinhorn S. C. Survival rates after enucleation of eyes with malignant melanoma. Am J Ophthalmol. 1979 Jun;87(6):761–765. doi: 10.1016/0002-9394(79)90349-0. [DOI] [PubMed] [Google Scholar]
  9. Stanford G. B., Reese A. B. Malignant cells in the blood of eye patients. Trans Am Acad Ophthalmol Otolaryngol. 1971 Jan-Feb;75(1):102–109. [PubMed] [Google Scholar]
  10. Zimmerman L. E., McLean I. W. An evaluation of enucleation in the management of uveal melanomas. Am J Ophthalmol. 1979 Jun;87(6):741–760. doi: 10.1016/0002-9394(79)90348-9. [DOI] [PubMed] [Google Scholar]
  11. Zimmerman L. E., McLean I. W., Foster W. D. Does enucleation of the eye containing a malignant melanoma prevent or accelerate the dissemination of tumour cells. Br J Ophthalmol. 1978 Jun;62(6):420–425. doi: 10.1136/bjo.62.6.420. [DOI] [PMC free article] [PubMed] [Google Scholar]
  12. Zimmerman L. E., McLean I. W., Foster W. D. Statistical analysis of follow-up data concerning uveal melanomas, and the influence of enucleation. Ophthalmology. 1980 Jun;87(6):557–564. doi: 10.1016/s0161-6420(80)35196-8. [DOI] [PubMed] [Google Scholar]

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