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. 1983 Aug;67(8):529–534. doi: 10.1136/bjo.67.8.529

Autosomal dominant iridogoniodysgenesis with associated somatic anomalies: four-generation family with Rieger's syndrome.

I A Chisholm, A E Chudley
PMCID: PMC1040113  PMID: 6871144

Abstract

A family extending over 4 generations showed iridogoniodysgenesis accompanied by somatic malformations inherited in an autosomal dominant fashion. Iridogoniodysgenesis was present in 10 members, of whom 5 had established glaucoma; 4 youthful members are likely to develop glaucoma. Somatic malformations were present in 5 members from the 3rd and 4th generations who did not manifest iridogoniodysgenesis. A possible polygenic basis is discussed, though the variable expression of an autosomal dominant inheritance is still the more likely explanation.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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