Skip to main content
NCBI home page
The British Journal of Ophthalmology logoLink to The British Journal of Ophthalmology
. 1983 Oct;67(10):700–704. doi: 10.1136/bjo.67.10.700

Neonatal chlamydial eye infection: an epidemiological and clinical study.

K Persson, R Rönnerstam, L Svanberg, M A Pohla
PMCID: PMC1040169  PMID: 6615756

Abstract

Neonatal chlamydial eye infection was detected in 39 cases of 281 infants with purulent conjunctivitis seen at the Department of Ophthalmology. Most cases of neonatal chlamydial eye infection (90%) were detected during the first month of life, and no case was found after 2 months of age. C. trachomatis was not isolated from any of 161 healthy control infants at 3-4 weeks of age. Genital chlamydial infection was demonstrated in 50% of the mothers to infected infants. Two of these women developed post-partum complications possibly due to chlamydial infection. Mothers of infected infants tended to be younger than average. Of 23 cases examined 2 years later, late sequelae were identified in 3.

Full text

PDF
700

Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. Chandler J. W., Alexander E. R., Pheiffer T. A., Wang S. P., Holmes K. K., English M. Ophthalmia neonatorum associated with maternal chlamydial infections. Trans Sect Ophthalmol Am Acad Ophthalmol Otolaryngol. 1977 Mar-Apr;83(2):302–308. [PubMed] [Google Scholar]
  2. Forster R. K., Dawson C. R., Schachter J. Late follow-up of patients with neonatal inclusion conjunctivitis. Am J Ophthalmol. 1970 Mar;69(3):467–472. doi: 10.1016/0002-9394(70)92284-1. [DOI] [PubMed] [Google Scholar]
  3. Freedman A., al-Hussaini M. K., Dunlop M. C., Emarah M. H., Garland J. A., Harper I. A., Jones B. R., Race J. W., Du Toit M. S., Treharne J. D. Infection by TRIC agent and other members of the Bedsonia group; with a note on Reiter's disease. II. Ophthalmia neonatorum due to TRIC agent. Trans Ophthalmol Soc U K. 1966;86:313–320. [PubMed] [Google Scholar]
  4. Frommell G. T., Rothenberg R., Wang S., McIntosh K. Chlamydial infection of mothers and their infants. J Pediatr. 1979 Jul;95(1):28–32. doi: 10.1016/s0022-3476(79)80077-3. [DOI] [PubMed] [Google Scholar]
  5. Goscienski P. J., Sexton R. R. Follow-up studies in neonatal inclusion conjunctivitis. Am J Dis Child. 1972 Aug;124(2):180–182. doi: 10.1001/archpedi.1972.02110140030003. [DOI] [PubMed] [Google Scholar]
  6. Hammerschlag M. R., Anderka M., Semine D. Z., McComb D., McCormack W. M. Prospective study of maternal and infantile infection with Chlamydia trachomatis. Pediatrics. 1979 Aug;64(2):142–148. [PubMed] [Google Scholar]
  7. Heggie A. D., Lumicao G. G., Stuart L. A., Gyves M. T. Chlamydia trachomatis infection in mothers and infants. A prospective study. Am J Dis Child. 1981 Jun;135(6):507–511. doi: 10.1001/archpedi.1981.02130300007005. [DOI] [PubMed] [Google Scholar]
  8. JONES B. R., COLLIER L. H., SMITH C. H. Isolation of virus from inclusion blennorrhoea. Lancet. 1959 May 2;1(7079):902–905. doi: 10.1016/s0140-6736(59)91307-8. [DOI] [PubMed] [Google Scholar]
  9. Mabey D. C., Whittle H. C. Genital and neonatal chlamydial infection in a trachoma endemic area. Lancet. 1982 Aug 7;2(8293):300–301. doi: 10.1016/s0140-6736(82)90273-2. [DOI] [PubMed] [Google Scholar]
  10. Meheus A., Delgadillo R., Widy-Wirski R., Piot P. Chlamydial ophthalmia neonatorum in Central Africa. Lancet. 1982 Oct 16;2(8303):882–882. doi: 10.1016/s0140-6736(82)90850-9. [DOI] [PubMed] [Google Scholar]
  11. Mordhorst C. H., Dawson C. Sequelae of neonatal inclusion conjunctivitis and associated disease in parents. Am J Ophthalmol. 1971 Apr;71(4):861–867. doi: 10.1016/0002-9394(71)90256-x. [DOI] [PubMed] [Google Scholar]
  12. Mordhorst C. H., Wang S. P., Grayston J. T. Childhood trachoma in a nonendemic area. Danish trachoma patients and their close contacts, 1963 to 1973. JAMA. 1978 Apr 28;239(17):1765–1771. doi: 10.1001/jama.239.17.1765. [DOI] [PubMed] [Google Scholar]
  13. Mourad A., Sweet R. L., Sugg N., Schachter J. Relative resistance to erythromycin in Chlamydia trachomatis. Antimicrob Agents Chemother. 1980 Nov;18(5):696–698. doi: 10.1128/aac.18.5.696. [DOI] [PMC free article] [PubMed] [Google Scholar]
  14. Mårdh P. A., Helin I., Bobeck S., Laurin J., Nilsson T. Colonisation of pregnant and puerperal women and neonates with Chlamydia trachomatis. Br J Vener Dis. 1980 Apr;56(2):96–100. doi: 10.1136/sti.56.2.96. [DOI] [PMC free article] [PubMed] [Google Scholar]
  15. Persson K., Rönnerstam R., Svanberg L., Holmberg L. Maternal and infantile infection with Chlamydia in a Swedish population. Acta Paediatr Scand. 1981 Jan;70(1):101–105. doi: 10.1111/j.1651-2227.1981.tb07180.x. [DOI] [PubMed] [Google Scholar]
  16. Rees E., Tait I. A., Hobson D., Karayiannis P., Lee N. Persistence of chlamydial infection after treatment for neonatal conjunctivitis. Arch Dis Child. 1981 Mar;56(3):193–198. doi: 10.1136/adc.56.3.193. [DOI] [PMC free article] [PubMed] [Google Scholar]
  17. Schachter J., Grossman M., Holt J., Sweet R., Goodner E., Mills J. Prospective study of chlamydial infection in neonates. Lancet. 1979 Aug 25;2(8139):377–380. doi: 10.1016/s0140-6736(79)90400-8. [DOI] [PubMed] [Google Scholar]
  18. Schachter J., Grossman M., Holt J., Sweet R., Spector S. Infection with Chlamydia trachomatis: involvement of multiple anatomic sites in neonates. J Infect Dis. 1979 Feb;139(2):232–234. doi: 10.1093/infdis/139.2.232. [DOI] [PubMed] [Google Scholar]
  19. Sowa S., Sowa J., Collier L. H. Investigation of neonatal conjunctivitis in the Gambia. Lancet. 1968 Aug 3;2(7562):243–247. doi: 10.1016/s0140-6736(68)92352-0. [DOI] [PubMed] [Google Scholar]
  20. Wager G. P., Martin D. H., Koutsky L., Eschenbach D. A., Daling J. R., Chiang W. T., Alexander E. R., Holmes K. K. Puerperal infectious morbidity: relationship to route of delivery and to antepartum Chlamydia trachomatis infection. Am J Obstet Gynecol. 1980 Dec 1;138(7 Pt 2):1028–1033. doi: 10.1016/0002-9378(80)91102-3. [DOI] [PubMed] [Google Scholar]
  21. Watson P. G., Gairdner D. TRIC agent as a cause of neonatal eye sepsis. Br Med J. 1968 Aug 31;3(5617):527–528. doi: 10.1136/bmj.3.5617.524-a. [DOI] [PMC free article] [PubMed] [Google Scholar]

Articles from The British Journal of Ophthalmology are provided here courtesy of BMJ Publishing Group

RESOURCES