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. 1983 Nov;67(11):755–758. doi: 10.1136/bjo.67.11.755

Familial exudative vitreoretinopathy associated with familial thrombocytopathy.

P R Chaudhuri, A R Rosenthal, D B Goulstine, D Rowlands, V E Mitchell
PMCID: PMC1040194  PMID: 6685528

Abstract

Two families with familial exudative vitreoretinopathy were studied in which platelet aggregation defects were found in all the affected members. The major defect observed was absent platelet aggregation with arachidonic acid. In addition platelet aggregation with collagen and adrenaline was reduced in one severely affected member. The implication of the platelet aggregation defect in the pathogenesis of this retinal vascular disorder is discussed.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. Brockhurst R. J., Albert D. M., Zakov Z. N. Pathologic findings in familial exudative vitreoretinopathy. Arch Ophthalmol. 1981 Dec;99(12):2143–2146. doi: 10.1001/archopht.1981.03930021019006. [DOI] [PubMed] [Google Scholar]
  2. Canny C. L., Oliver G. L. Fluorescein angiographic findings in familial exudative vitreoretinopathy. Arch Ophthalmol. 1976 Jul;94(7):1114–1120. doi: 10.1001/archopht.1976.03910040034006. [DOI] [PubMed] [Google Scholar]
  3. Criswick V. G., Schepens C. L. Familial exudative vitreoretinopathy. Am J Ophthalmol. 1969 Oct;68(4):578–594. doi: 10.1016/0002-9394(69)91237-9. [DOI] [PubMed] [Google Scholar]
  4. Flower R. W., Blake D. A. Retrolental fibroplasia: evidence for a role of the prostaglandin cascade in the pathogenesis of oxygen-induced retinopathy in the newborn beagle. Pediatr Res. 1981 Sep;15(9):1293–1302. doi: 10.1203/00006450-198109000-00013. [DOI] [PubMed] [Google Scholar]
  5. Gow J., Oliver G. L. Familial exudative vitreoretinopathy. An expanded view. Arch Ophthalmol. 1971 Aug;86(2):150–155. doi: 10.1001/archopht.1971.01000010152007. [DOI] [PubMed] [Google Scholar]
  6. Moncada S., Vane J. R. Unstable metabolites of arachidonic acid and their role in haemostasis and thrombosis. Br Med Bull. 1978 May;34(2):129–135. doi: 10.1093/oxfordjournals.bmb.a071482. [DOI] [PubMed] [Google Scholar]
  7. Ober R. R., Bird A. C., Hamilton A. M., Sehmi K. Autosomal dominant exudative vitreoretinopathy. Br J Ophthalmol. 1980 Feb;64(2):112–120. doi: 10.1136/bjo.64.2.112. [DOI] [PMC free article] [PubMed] [Google Scholar]

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