Abstract
The anterior chambers of 27 rabbit eyes were perfused at constant pressure with room temperature (25 degrees C) or cooled (11 degrees C) balanced salt solution at constant flow rates of 4.8 ml/min or 8.5 ml/min. Intraocular temperature changes in the anterior chamber, anterior vitreous, mid vitreous, and posterior vitreous and on the retina surface were monitored with an intraocular thermocouple probe. Perfusion of the anterior chamber of the pigmented rabbit eye with cooled fluid significantly reduced the temperature of the anterior chamber and anterior vitreous and even that of the retina. Both an increase in the rate of perfusion and a lowering of the perfusion temperature enhanced the cooling effect. The observed decrease in temperatures returned to approximately normal 4 minutes following the cessation of perfusion.
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Selected References
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- Andrew J. H. The Conduction of Heat to the Interior of the Eye and Orbit from a Constant Temperature Applied to the Cornea. Trans Am Ophthalmol Soc. 1935;33:407–413. [PMC free article] [PubMed] [Google Scholar]
- Binkhorst C. D., Nygaard P., Loones L. H. Specular microscopy of the corneal endothelium and lens implant surgery. Am J Ophthalmol. 1978 May;85(5 Pt 1):597–605. doi: 10.1016/s0002-9394(14)77090-4. [DOI] [PubMed] [Google Scholar]
- Bourne W. M., Brubaker R. F., O'Fallon W. M. Use of air to decrease endothelial cell loss during intraocular lens implantation. Arch Ophthalmol. 1979 Aug;97(8):1473–1475. doi: 10.1001/archopht.1979.01020020135009. [DOI] [PubMed] [Google Scholar]
- Fatt I., Forester J. F. Errors in eye tissue temperature measurements when using a metallic probe. Exp Eye Res. 1972 Nov;14(3):270–276. doi: 10.1016/0014-4835(72)90013-9. [DOI] [PubMed] [Google Scholar]
- Fisk R. L., Gelfand E. T., Callaghan J. C. Hypothermic coronary perfusion for intraoperative cardioplegia. Ann Thorac Surg. 1977 Jan;23:58–61. doi: 10.1016/s0003-4975(10)64070-2. [DOI] [PubMed] [Google Scholar]
- Freeman R. D., Fatt I. Environmental influences on ocular temperature. Invest Ophthalmol. 1973 Aug;12(8):596–602. [PubMed] [Google Scholar]
- Fuller D., Machemer R., Knighton R. W. Retinal damage produced by intraocular fiber optic light. Am J Ophthalmol. 1978 Apr;85(4):519–537. doi: 10.1016/s0002-9394(14)75250-x. [DOI] [PubMed] [Google Scholar]
- Henkes H. E. Photic injury to the retina and the manifestation of acute posterior multifocal placoid pigment epitheliopathy. Doc Ophthalmol. 1977 Sep 30;44(1):113–120. doi: 10.1007/BF00171462. [DOI] [PubMed] [Google Scholar]
- Irvine A. R., Kratz R. P., O'Donnell J. J. Endothelial damage with phacoemulsification and intraocular lens implantation. Arch Ophthalmol. 1978 Jun;96(6):1023–1026. doi: 10.1001/archopht.1978.03910050547011. [DOI] [PubMed] [Google Scholar]
- Lanum J. The damaging effects of light on the retina. Empirical findings, theoretical and practical implications. Surv Ophthalmol. 1978 Jan-Feb;22(4):221–249. doi: 10.1016/0039-6257(78)90070-x. [DOI] [PubMed] [Google Scholar]
- Lawwill T., Crockett S., Currier G. Retinal damage secondary to chronic light exposure, thresholds and mechanisms. Doc Ophthalmol. 1977 Dec 30;44(2):379–402. doi: 10.1007/BF00230089. [DOI] [PubMed] [Google Scholar]
- McDowall D. G. The current usage of hypothermia in British neurosurgery. Br J Anaesth. 1971 Nov;43(11):1084–1087. doi: 10.1093/bja/43.11.1084. [DOI] [PubMed] [Google Scholar]
- McGill C., Taylor B., Acland R., Flint L. Effects of cooling and intraluminal antiseptics on ischemia in small bowel and colon. Surg Forum. 1977;28:424–425. [PubMed] [Google Scholar]
- McKechnie N. M., Johnson N. F. Light damage to the retina. Albrecht Von Graefes Arch Klin Exp Ophthalmol. 1977 Sep 28;203(3-4):283–292. doi: 10.1007/BF00409834. [DOI] [PubMed] [Google Scholar]
- Robertson D. M., Erickson G. J. The effect of prolonged indirect ophthalmoscopy on the human eye. Am J Ophthalmol. 1979 May;87(5):652–661. doi: 10.1016/0002-9394(79)90299-x. [DOI] [PubMed] [Google Scholar]
- Rosenbluth R. F., Fatt I. Temperature measurements in the eye. Exp Eye Res. 1977 Oct;25(4):325–341. doi: 10.1016/0014-4835(77)90100-2. [DOI] [PubMed] [Google Scholar]
- SCHWARTZ B. ENVIRONMENTAL TEMPERATURE AND THE OCULAR TEMPERATURE GRADIENT. Arch Ophthalmol. 1965 Aug;74:237–243. doi: 10.1001/archopht.1965.00970040239022. [DOI] [PubMed] [Google Scholar]
- SCHWARTZ B., FELLER M. R. Temperature gradients in the rabbit eye. Invest Ophthalmol. 1962 Aug;1:513–521. [PubMed] [Google Scholar]
- SCHWARTZ B. THE EFFECT OF LID CLOSURE UPON THE OCULAR TEMPERATURE GRADIENT. Invest Ophthalmol. 1964 Feb;3:100–106. [PubMed] [Google Scholar]
- SHUMWAY N. E., LOWER R. R., STOFER R. C. Selective hypothermia of the heart in anoxic cardiac arrest. Surg Gynecol Obstet. 1959 Dec;109:750–754. [PubMed] [Google Scholar]
- Sugar J., Mitchelson J., Kraff M. Endothelial trauma and cell loss from intraocular lens insertion. Arch Ophthalmol. 1978 Mar;96(3):449–450. doi: 10.1001/archopht.1978.03910050225006. [DOI] [PubMed] [Google Scholar]
- Swan H. Clinical hypothermia: a lady with a past and some promise for the future. Surgery. 1973 May;73(5):736–758. [PubMed] [Google Scholar]
- Wickham J. E., Hanley H. G., Joekes A. M. Regional renal hypothermia. Br J Urol. 1967 Dec;39(6):727–743. doi: 10.1111/j.1464-410x.1967.tb09856.x. [DOI] [PubMed] [Google Scholar]
- Wolin L. R., Massopurst L. C., Jr Selective cooling of the eye. Effects on evoked potentials of the visual system. Arch Ophthalmol. 1966 Nov;76(5):723–728. doi: 10.1001/archopht.1966.03850010725020. [DOI] [PubMed] [Google Scholar]
