Abstract
The incidence and severity of cataract were studied in 37 children who had completed treatment for acute lymphoblastic leukaemia. Twelve (32%) had posterior subcapsular lens opacities. Treatment had included corticosteroids and cranial irradiation, but no dose relationship was evident. The boys were more severely affected than the girls. Although none of the lens opacities was optically significant, clinicians should be aware of the potential risk to vision.
Full text
PDF
Selected References
These references are in PubMed. This may not be the complete list of references from this article.
- BLACK R. L., OGLESBY R. B., VON SALLMANN L., BUNIM J. J. Posterior subcapsular cataracts induced by corticosteroids in patients with rheumatoid arthritis. JAMA. 1960 Sep 10;174:166–171. doi: 10.1001/jama.1960.63030020005014. [DOI] [PubMed] [Google Scholar]
- CREWS S. J. Posterior subcapsular lens opacities in patients on longterm corticosteroid therapy. Br Med J. 1963 Jun 22;1(5346):1644–1647. doi: 10.1136/bmj.1.5346.1642. [DOI] [PMC free article] [PubMed] [Google Scholar]
- DIKSHIT S. K., AVASTHI P. N. POSTERIOR LENTICULAR OPACITIES IN CHILDREN ON CORTICOSTEROID THERAPY. Indian J Pediatr. 1965 Mar;32:93–96. doi: 10.1007/BF02756568. [DOI] [PubMed] [Google Scholar]
- Fine R. N., Offner G., Wilson W. A., Mickey M. R., Pennisi A. F., Malekzadeh M. H. Posterior subcapsular cataracts: posttransplantation in children. Ann Surg. 1975 Nov;182(5):585–589. doi: 10.1097/00000658-197511000-00009. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Fraunfelder F. T., Meyer S. M. Ocular toxicity of antineoplastic agents. Ophthalmology. 1983 Jan;90(1):1–3. doi: 10.1016/s0161-6420(83)34600-5. [DOI] [PubMed] [Google Scholar]
- HAVRE D. C. CATARACTS IN CHILDREN ON LONG-TERM CORTICOSTEROID THERAPY. Arch Ophthalmol. 1965 Jun;73:818–821. doi: 10.1001/archopht.1965.00970030820012. [DOI] [PubMed] [Google Scholar]
- Kobayashi Y., Akaishi K., Nishio T., Kobayashi Y., Kimura Y. Posterior subcapsular cataract in nephrotic children receiving steroid therapy. Am J Dis Child. 1974 Nov;128(5):671–673. doi: 10.1001/archpedi.1974.02110300081010. [DOI] [PubMed] [Google Scholar]
- MERRIAM G. R., Jr, FOCHT E. F. A clinical study of radiation cataracts and the relationship to dose. Am J Roentgenol Radium Ther Nucl Med. 1957 May;77(5):759–785. [PubMed] [Google Scholar]
- Macfaul P. A., Bedford M. A. Ocular complications after therapeutic irradiation. Br J Ophthalmol. 1970 Apr;54(4):237–247. doi: 10.1136/bjo.54.4.237. [DOI] [PMC free article] [PubMed] [Google Scholar]