Abstract
The case is described of a 39-year-old man with previously undiagnosed chronic schizophrenia and with bilateral keratomalacia secondary to his bizarre diet. He presented with a perforation of the right cornea which required an emergency penetrating keratoplasty. The difficulties of clinical management of a patient with an overt psychosis and the use of serum retinol levels to monitor treatment are described. Causes of vitamin A deficiency seen in Great Britain are discussed.
Full text
PDF



Selected References
These references are in PubMed. This may not be the complete list of references from this article.
- ARDEN G. B., KOLB H. ELECTROPHYSIOLOGICAL INVESTIGATIONS IN RETINAL METABOLIC DISEASE: THEIR RANGE AND APPLICATION. Exp Eye Res. 1964 Dec;3:334–347. doi: 10.1016/s0014-4835(64)80041-5. [DOI] [PubMed] [Google Scholar]
- Bors F., Fells P. Reversal of the complications of self-induced vitamin A deficiency. Br J Ophthalmol. 1971 Mar;55(3):210–214. doi: 10.1136/bjo.55.3.210. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Brown G. C., Felton S. M., Benson W. E. Reversible night blindness associated with intestinal bypass surgery. Am J Ophthalmol. 1980 Jun;89(6):776–779. doi: 10.1016/0002-9394(80)90164-6. [DOI] [PubMed] [Google Scholar]
- Carney E. A., Russell R. M. Correlation of dark adaptation test results with serum vitamin A levels in diseased adults. J Nutr. 1980 Mar;110(3):552–557. doi: 10.1093/jn/110.3.552. [DOI] [PubMed] [Google Scholar]
- Main A. N., Mills P. R., Russell R. I., Bronte-Stewart J., Nelson L. M., McLelland A., Shenkin A. Vitamin A deficiency in Crohn's disease. Gut. 1983 Dec;24(12):1169–1175. doi: 10.1136/gut.24.12.1169. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Russell R. M., Smith V. C., Multack R., Krill A. E., Rosenberg I. H. Dark-adaptation testing for diagnosis of subclinical vitamin-A deficiency and evaluation of therapy. Lancet. 1973 Nov 24;2(7839):1161–1164. doi: 10.1016/s0140-6736(73)92935-8. [DOI] [PubMed] [Google Scholar]
- Walt R. P., Kemp C. M., Lyness L., Bird A. C., Sherlock S. Vitamin A treatment for night blindness in primary biliary cirrhosis. Br Med J (Clin Res Ed) 1984 Apr 7;288(6423):1030–1031. doi: 10.1136/bmj.288.6423.1030. [DOI] [PMC free article] [PubMed] [Google Scholar]
