Abstract
Intraocular pressure was measured in 24 patients undergoing elective cardiopulmonary bypass surgery. There was a rapid rise when the bypass circulation began, and this was maintained for about 30 minutes. A simultaneous drop in arterial perfusion pressure and packed cell volume occurred. We suggest that marked haemodilution is responsible for this effect, through increased ocular blood flow and low colloidal osmotic pressure. The possible aetiological significance in relation to ischaemic optic neuropathy complicating cardiopulmonary bypass is discussed.
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Selected References
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- DAVSON H., THOMASSEN T. L. The effect of intravenous infusion of hypertonic saline on the intra-ocular pressure. Br J Ophthalmol. 1950 Jun;34(6):355–359. doi: 10.1136/bjo.34.6.355. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Hørven I., Lundar T., Lilleaasen P., Hysing E., Stokke O. The effect of haemodilution on arterial blood pressure, central venous pressure, intracranial and intra-ocular pressures in pigs. Scand J Thorac Cardiovasc Surg. 1981;15(3):273–277. doi: 10.3109/14017438109100586. [DOI] [PubMed] [Google Scholar]
- Kaskel D., Fink H. Einfluss einiger Kreislaufgrössen auf den Augeninnendruck. Adv Ophthalmol. 1975;29:190–202. [PubMed] [Google Scholar]
- Lilleaasen P., Hørven I. Intra-ocular pressure levels during extracorporeal circulation in man. Scand J Thorac Cardiovasc Surg. 1982;16(1):51–53. doi: 10.3109/14017438209100609. [DOI] [PubMed] [Google Scholar]
- Lundar T., Lindegaard K. F., Frøysaker T., Aaslid R., Wiberg J., Nornes H. Cerebral perfusion during nonpulsatile cardiopulmonary bypass. Ann Thorac Surg. 1985 Aug;40(2):144–150. doi: 10.1016/s0003-4975(10)60007-0. [DOI] [PubMed] [Google Scholar]
- Samuel J. R., Beaugié A. Effect of carbon dioxide on the intraocular pressure in man during general anaesthesia. Br J Ophthalmol. 1974 Jan;58(1):62–67. doi: 10.1136/bjo.58.1.62. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Sweeney P. J., Breuer A. C., Selhorst J. B., Waybright E. A., Furlan A. J., Lederman R. J., Hanson M. R., Tomsak R. Ischemic optic neuropathy: a complication of cardiopulmonary bypass surgery. Neurology. 1982 May;32(5):560–562. doi: 10.1212/wnl.32.5.560. [DOI] [PubMed] [Google Scholar]
- Tomsak R. L. Ischemic optic neuropathy associated with retinal embolism. Am J Ophthalmol. 1985 May 15;99(5):590–592. doi: 10.1016/s0002-9394(14)77966-8. [DOI] [PubMed] [Google Scholar]