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. 1987 Apr;71(4):295–300. doi: 10.1136/bjo.71.4.295

Ophthalmia neonatorum: study of a decade of experience at the Mount Sinai Hospital.

V N Jarvis, R Levine, P A Asbell
PMCID: PMC1041146  PMID: 3580342

Abstract

We reviewed the charts of neonates who received a diagnosis of conjunctivitis or ophthalmia neonatorum during a 10-year period at the Mount Sinai Hospital, New York City. Ninety-five cases were discovered, four of these were born elsewhere and were not subject to our protocol, which at present consists of intramuscular penicillin and topical tetracycline ointment (1%). The 91 cases represent an incidence of 3.1 cases per 1000 live births (9.1/year), an incidence approximately equal to that reported in other published studies. The clinical characteristics examined were: age, sex, race, birth weight, gestational age, Apgar scores, presence or absence of fever or other systemic illnesses, complications, type of delivery, time of year, incubation period, presence and type of discharge, uni- or bilaterality, Gram stain, Giemsa stain, culture results, antibiotic disc sensitivities, cervical culture, antibiotic therapy, sequelae, and type of prophylaxis received. Seven aetiological diagnostic categories were established: gonococcal (3%), chlamydial (3%), staphylococcal (30%), other pathogens (25%), chemical conjunctivitis (7%), culture negative/normal flora (22%), and unobtainable (10%). This distribution differs from others published. In contrast with other studies, moreover, we found few gonococcal and no chlamydial cases in neonates subject to the Mount Sinai Hospital treatment protocol. Correlation of clinical characteristics and aetiological categories showed no statistically significant trend. So far there have been no cases of ophthalmia neonatorum, treated as on our protocol, caused by penicillin resistant gonococci or chlamydiae.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. Armstrong J. H., Zacarias F., Rein M. F. Ophthalmia neonatorum: a chart review. Pediatrics. 1976 Jun;57(6):884–892. [PubMed] [Google Scholar]
  2. BICKEL J. E. Sodium sulfacetimide for the prophylaxis of gonorrheal ophthalmia neonatorum; preliminary report. J Pediatr. 1950 Dec;37(6):854–857. doi: 10.1016/s0022-3476(50)80046-x. [DOI] [PubMed] [Google Scholar]
  3. CHRISTIAN J. R. Comparison of ocular reactions with the use of silver nitrate and erythromycin ointment in ophthalmia neonatorum prophylaxis. J Pediatr. 1960 Jul;57:55–60. doi: 10.1016/s0022-3476(60)80210-7. [DOI] [PubMed] [Google Scholar]
  4. DUMONT P., DE HAZE M. Ophtalmie des nouveau-nés. Brux Med. 1955 Oct 23;35(43):2125–2137. [PubMed] [Google Scholar]
  5. GREENBERG M., VANDOW J. E. Ophthalmia neonatorum: evaluation of different methods of prophylaxis in New York City. Am J Public Health Nations Health. 1961 Jun;51:836–845. doi: 10.2105/ajph.51.6.836. [DOI] [PMC free article] [PubMed] [Google Scholar]
  6. MARGILETH A. M. Comparison of ocular reactions using penicillin and bacitracin ointments in ophthalmia neonatorum prophylaxis. J Pediatr. 1957 Dec;51(6):646–651. doi: 10.1016/s0022-3476(57)80097-3. [DOI] [PubMed] [Google Scholar]
  7. MATHIEU P. L., Jr Comparison study: silver nitrate and oxytetracycline in newborn eyes; a comparison of the incidence of conjunctivitis following the instillation of silver nitrate or oxytetracycline into the eyes of newborn infants. AMA J Dis Child. 1958 Jun;95(6):609–611. doi: 10.1001/archpedi.1958.02060050613003. [DOI] [PubMed] [Google Scholar]
  8. Mooney B. R., Green J. A., Epstein B. J., Hashisaki P. A. Non-gonococcal ophthalmitis associated with erythromycin ointment prophylaxis of gonococcal ophthalmia neonatorum. Infect Control. 1984 Mar;5(3):138–140. doi: 10.1017/s0195941700060008. [DOI] [PubMed] [Google Scholar]
  9. POSNER A. C., ANDERSON G. D., PRIGOT A. Observations on the prophylaxis of ophthalmia neonatorum in a Municipal Hospital. Antibiot Annu. 1958;6:134–137. [PubMed] [Google Scholar]
  10. Raucher H. S., Newton M. J. New issues in the prevention and treatment of ophthalmia neonatorum. Ann Ophthalmol. 1983 Nov;15(11):1004, 1006-9. [PubMed] [Google Scholar]
  11. Raucher H. S., Newton M. J., Stern R. H. Ophthalmia neonatorum caused by penicillinase-producing Neisseria gonorrhoeae. J Pediatr. 1982 Jun;100(6):925–926. doi: 10.1016/s0022-3476(82)80516-7. [DOI] [PubMed] [Google Scholar]
  12. Stenson S., Newman R., Fedukowicz H. Conjunctivitis in the newborn: observations on incidence, cause, and prophylaxis. Ann Ophthalmol. 1981 Mar;13(3):329–334. [PubMed] [Google Scholar]
  13. WACHTER H. E., PENNOYER M. M. Prophylaxis in the eyes of newborn infants; a comparison of silver nitrate and erythromycin. Mo Med. 1956 Mar;53(3):187–190. [PubMed] [Google Scholar]

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