Skip to main content
NCBI home page
The British Journal of Ophthalmology logoLink to The British Journal of Ophthalmology
. 1987 Aug;71(8):565–569. doi: 10.1136/bjo.71.8.565

Ophthalmic findings in a group of ambulatory patients infected by human immunodeficiency virus (HIV): a prospective study.

R C Humphry 1, J N Weber 1, R J Marsh 1
PMCID: PMC1041234  PMID: 2820464

Abstract

Twenty-eight patients with either the acquired immune deficiency syndrome (AIDS) or persistent generalised lymphadenopathy (PGL) were studied prospectively as outpatients for up to one year. Six patients had fundal cotton wool spots at some stage of their follow-up and all six suffered opportunistic infections associated with AIDS. We suggest that ocular abnormalities may be prognostic for opportunistic infection in AIDS and discuss the wide range of ophthalmic complications consequent to HIV infection.

Full text

PDF
565

Images in this article

567Image
on p.567
568Image
on p.568
568Image
on p.568

Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. Bach M. C., Bagwell S. P., Knapp N. P., Davis K. M., Hedstrom P. S. 9-(1,3-Dihydroxy-2-propoxymethyl)guanine for cytomegalovirus infections in patients with the acquired immunodeficiency syndrome. Ann Intern Med. 1985 Sep;103(3):381–382. doi: 10.7326/0003-4819-103-3-381. [DOI] [PubMed] [Google Scholar]
  2. Felsenstein D., D'Amico D. J., Hirsch M. S., Neumeyer D. A., Cederberg D. M., de Miranda P., Schooley R. T. Treatment of cytomegalovirus retinitis with 9-[2-hydroxy-1-(hydroxymethyl)ethoxymethyl]guanine. Ann Intern Med. 1985 Sep;103(3):377–380. doi: 10.7326/0003-4819-103-3-377. [DOI] [PubMed] [Google Scholar]
  3. Fujikawa L. S., Salahuddin S. Z., Palestine A. G., Masur H., Nussenblatt R. B., Gallo R. C. Isolation of human T-lymphotropic virus type III from the tears of a patient with the acquired immunodeficiency syndrome. Lancet. 1985 Sep 7;2(8454):529–530. doi: 10.1016/s0140-6736(85)90464-7. [DOI] [PubMed] [Google Scholar]
  4. Gottlieb M. S., Schroff R., Schanker H. M., Weisman J. D., Fan P. T., Wolf R. A., Saxon A. Pneumocystis carinii pneumonia and mucosal candidiasis in previously healthy homosexual men: evidence of a new acquired cellular immunodeficiency. N Engl J Med. 1981 Dec 10;305(24):1425–1431. doi: 10.1056/NEJM198112103052401. [DOI] [PubMed] [Google Scholar]
  5. Haverkos H. W., Gotlieb M. S., Killen J. Y., Edelman R. Classification of HTLV-III/LAV-related diseases. J Infect Dis. 1985 Nov;152(5):1095–1095. doi: 10.1093/infdis/152.5.1095. [DOI] [PubMed] [Google Scholar]
  6. Holland G. N., Gottlieb M. S., Yee R. D., Schanker H. M., Pettit T. H. Ocular disorders associated with a new severe acquired cellular immunodeficiency syndrome. Am J Ophthalmol. 1982 Apr;93(4):393–402. doi: 10.1016/0002-9394(82)90127-1. [DOI] [PubMed] [Google Scholar]
  7. Holland G. N., Pepose J. S., Pettit T. H., Gottlieb M. S., Yee R. D., Foos R. Y. Acquired immune deficiency syndrome. Ocular manifestations. Ophthalmology. 1983 Aug;90(8):859–873. doi: 10.1016/s0161-6420(83)80009-8. [DOI] [PubMed] [Google Scholar]
  8. Miller B., Stansfield S. K., Zack M. M., Curran J. W., Kaplan J. E., Schonberger L. B., Falk H., Spira T. J., Mildvan D. The syndrome of unexplained generalized lymphadenopathy in young men in New York City. Is it related to the acquired immune deficiency syndrome? JAMA. 1984 Jan 13;251(2):242–246. [PubMed] [Google Scholar]
  9. Moore J. W. The patch clamp: single-channel recording. Science. 1984 Apr 6;224(4644):50–51. doi: 10.1126/science.224.4644.50. [DOI] [PubMed] [Google Scholar]
  10. Pepose J. S., Nestor M. S., Holland G. N., Cochran A. J., Foos R. Y. An analysis of retinal cotton-wool spots and cytomegalovirus retinitis in the acquired immunodeficiency syndrome. Am J Ophthalmol. 1983 Jan;95(1):118–120. doi: 10.1016/0002-9394(83)90341-0. [DOI] [PubMed] [Google Scholar]
  11. Popovic M., Sarngadharan M. G., Read E., Gallo R. C. Detection, isolation, and continuous production of cytopathic retroviruses (HTLV-III) from patients with AIDS and pre-AIDS. Science. 1984 May 4;224(4648):497–500. doi: 10.1126/science.6200935. [DOI] [PubMed] [Google Scholar]
  12. Rosenberg P. R., Uliss A. E., Friedland G. H., Harris C. A., Small C. B., Klein R. S. Acquired immunodeficiency syndrome. Ophthalmic manifestations in ambulatory patients. Ophthalmology. 1983 Aug;90(8):874–878. [PubMed] [Google Scholar]
  13. Sarngadharan M. G., Popovic M., Bruch L., Schüpbach J., Gallo R. C. Antibodies reactive with human T-lymphotropic retroviruses (HTLV-III) in the serum of patients with AIDS. Science. 1984 May 4;224(4648):506–508. doi: 10.1126/science.6324345. [DOI] [PubMed] [Google Scholar]
  14. Schuman J. S., Friedman A. H. Retinal manifestations of the acquired immune deficiency syndrome (AIDS): cytomegalovirus, candida albicans, cryptococcus, toxoplasmosis and Pneumocystis carinii. Trans Ophthalmol Soc U K. 1983;103(Pt 2):177–190. [PubMed] [Google Scholar]

Articles from The British Journal of Ophthalmology are provided here courtesy of BMJ Publishing Group

RESOURCES