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. 1987 Oct;71(10):748–752. doi: 10.1136/bjo.71.10.748

Intraocular reticulum cell sarcoma: diagnosis by choroidal biopsy.

M H Kirmani 1, E L Thomas 1, N A Rao 1, R P Laborde 1
PMCID: PMC1041299  PMID: 3314978

Abstract

A patient with uveitis and retinal pigment epithelial detachments underwent an extensive medical examination and pars plana vitrectomy in an attempt to confirm the clinical diagnosis of reticulum cell sarcoma. None of these examinations revealed the presence of malignancy. Transscleral biopsy of subretinal lesions confirmed the histopathological diagnosis of reticulum cell sarcoma. The patient was begun on systemic chemotherapy and external beam radiation to the eye and orbit, with resultant preservation of the eye, vision, and probable extension of life because of early detection of reticulum cell sarcoma by choroidal biopsy. This technique may be advantageous in the diagnosis cases of eyes with clinical evidence of reticulum cell sarcoma, no systemic signs of malignancy, and negative vitreous biopsies.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. Appen R. E. Posterior uveitis and primary cerebral reticulum cell sarcoma. Arch Ophthalmol. 1975 Feb;93(2):123–124. doi: 10.1001/archopht.1975.01010020129006. [DOI] [PubMed] [Google Scholar]
  2. BURSTEIN S. D., KERNOHAN J. W., UIHLEIN A. Neoplasms of the reticuloendothelial system of the brain. Cancer. 1963 Mar;16:289–305. doi: 10.1002/1097-0142(196303)16:3<289::aid-cncr2820160304>3.0.co;2-z. [DOI] [PubMed] [Google Scholar]
  3. Barr C. C., Green W. R., Payne J. W., Knox D. L., Jensen A. D., Thompson R. L. Intraocular reticulum-cell sarcoma: clinico-pathologic study of four cases and review of the literature. Surv Ophthalmol. 1975 Jan-Feb;19(4):224–239. [PubMed] [Google Scholar]
  4. Carroll D. M., Franklin R. M. Vitreous biopsy in uveitis of unknown cause. Retina. 1981;1(3):245–251. doi: 10.1097/00006982-198101030-00022. [DOI] [PubMed] [Google Scholar]
  5. Char D. H., Margolis L., Newman A. B. Ocular reticulum cell sarcoma. Am J Ophthalmol. 1981 Apr;91(4):480–483. doi: 10.1016/0002-9394(81)90236-1. [DOI] [PubMed] [Google Scholar]
  6. Constable I. J., Slatter D. H., Horne R. Chorioretinal biopsy in dogs. Invest Ophthalmol Vis Sci. 1980 Jun;19(6):603–609. [PubMed] [Google Scholar]
  7. Constable L. J., Chester G. H., Horne R., Harriott J. F. Human chorioretinal biopsy under controlled systemic hypotensive anaesthesia. Br J Ophthalmol. 1980 Aug;64(8):559–564. doi: 10.1136/bjo.64.8.559. [DOI] [PMC free article] [PubMed] [Google Scholar]
  8. Fisher D., Mantell B. S., Urich H. The clinical diagnosis and treatment of microgliomatosis: report of a case. J Neurol Neurosurg Psychiatry. 1969 Oct;32(5):474–478. doi: 10.1136/jnnp.32.5.474. [DOI] [PMC free article] [PubMed] [Google Scholar]
  9. Gass J. D., Sever R. J., Grizzard W. S., Clarkson J. G., Blumenkranz M., Wind C. A., Shugarman R. Multifocal pigment epithelial detachments by reticulum cell sarcoma. A characteristic funduscopic picture. Retina. 1984 Summer-Fall;4(3):135–143. doi: 10.1097/00006982-198400430-00001. [DOI] [PubMed] [Google Scholar]
  10. Griffin J. R., Straatsma B. R., Kreiger A. E. Transvitreal chorioretinal biopsy in the rabbit. Am J Ophthalmol. 1975 Jan;79(1):25–38. doi: 10.1016/0002-9394(75)90452-3. [DOI] [PubMed] [Google Scholar]
  11. Jakobiec F. A., Williams P., Wolff A. M. Reticulum cell sarcoma (histiocytic lymphoma) of the orbit. Surv Ophthalmol. 1978 Jan-Feb;22(4):255–270. doi: 10.1016/0039-6257(78)90072-3. [DOI] [PubMed] [Google Scholar]
  12. Kattah J. C., Jenkins R. B., Pilkerton R., Rao N. A., Manz H. J., Frazer M. Multifocal primary ocular and central nervous system malignant lymphoma. Ann Ophthalmol. 1981 May;13(5):589–593. [PubMed] [Google Scholar]
  13. Kennerdell J. S., Johnson B. L., Wisotzkey H. M. Vitreous cellular reaction. Association with reticulum cell sarcoma of brain. Arch Ophthalmol. 1975 Dec;93(12):1341–1345. doi: 10.1001/archopht.1975.01010020967006. [DOI] [PubMed] [Google Scholar]
  14. Kim E. W., Zakov Z. N., Albert D. M., Smith T. R., Craft J. L. Intraocular reticulum cell sarcoma: a case report and literature review. Albrecht Von Graefes Arch Klin Exp Ophthalmol. 1979 Jan 15;209(3):167–178. doi: 10.1007/BF00414609. [DOI] [PubMed] [Google Scholar]
  15. Klingele T. G., Hogan M. J. Ocular reticulum cell sarcoma. Am J Ophthalmol. 1975 Jan;79(1):39–47. doi: 10.1016/0002-9394(75)90453-5. [DOI] [PubMed] [Google Scholar]
  16. Lang G. K., Surer J. L., Green W. R., Finkelstein D., Michels R. G., Maumenee A. E. Ocular reticulum cell sarcoma. Clinicopathologic correlation of a case with multifocal lesions. Retina. 1985 Spring-Summer;5(2):79–86. [PubMed] [Google Scholar]
  17. Michels R. G., Knox D. L., Erozan Y. S., Green W. R. Intraocular reticulum cell sarcoma. Diagnosis by pars plana vitrectomy. Arch Ophthalmol. 1975 Dec;93(12):1331–1335. doi: 10.1001/archopht.1975.01010020961005. [DOI] [PubMed] [Google Scholar]
  18. Minckler D. S., Font R. L., Zimmerman L. E. Uveitis and reticulum cell sarcoma of brain with bilateral neoplastic seeding of vitreous without retinal or uveal involvement. Am J Ophthalmol. 1975 Sep;80(3 Pt 1):433–439. doi: 10.1016/0002-9394(75)90531-0. [DOI] [PubMed] [Google Scholar]
  19. Neault R. W., Van Scoy R. E., Okazaki H., MacCarty C. S. Uveitis associated with isolated reticulum cell sarcoma of the brain. Am J Ophthalmol. 1972 Mar;73(3):431–436. doi: 10.1016/0002-9394(72)90072-4. [DOI] [PubMed] [Google Scholar]
  20. Peyman G. A., Juarez C. P., Raichand M. Full-thickness eye-wall biopsy: long-term results in 9 patients. Br J Ophthalmol. 1981 Oct;65(10):723–726. doi: 10.1136/bjo.65.10.723. [DOI] [PMC free article] [PubMed] [Google Scholar]
  21. Rosenbaum T. J., MacCarty C. S., Buettner H. Uveitis and cerebral reticulum-cell sarcoma (large-cell lymphoma). Case report. J Neurosurg. 1979 May;50(5):660–664. doi: 10.3171/jns.1979.50.5.0660. [DOI] [PubMed] [Google Scholar]
  22. Schaumburg H. H., Plank C. R., Adams R. D. The reticulum cell sarcoma--microglioma group of brain tumours. A consideration of their clinical features and therapy. Brain. 1972;95(2):199–212. doi: 10.1093/brain/95.2.199. [DOI] [PubMed] [Google Scholar]
  23. Sullivan S. F., Dallow R. I. Intraocular reticulum cell sarcoma: its dramatic response to systemic chemotherapy and its angiogenic potential. Ann Ophthalmol. 1977 Apr;9(4):401–406. [PubMed] [Google Scholar]
  24. Vogel M. H., Font R. L., Zimmerman L. E., Levine R. A. Reticulum cell sarcoma of the retina and uvea. Report of six cases and review of the literature. Am J Ophthalmol. 1968 Aug;66(2):205–215. doi: 10.1016/0002-9394(68)92065-5. [DOI] [PubMed] [Google Scholar]

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