Skip to main content
NCBI home page
The British Journal of Ophthalmology logoLink to The British Journal of Ophthalmology
. 1987 Oct;71(10):782–786. doi: 10.1136/bjo.71.10.782

Parameters for neodymium-YAG laser trabeculotomy: an in-vitro study.

G N Dutton 1, S A Cameron 1, D Allan 1, R Thomas 1
PMCID: PMC1041306  PMID: 3676150

Abstract

A Biophysic Médical Nanolas Q-Switched pulsed neodymium-YAG laser has been used to produce lesions in human trabecular meshwork in vitro. Sectors of corneoscleral tissue containing trabecular meshwork were suspended in a waterbath which had had a Trokel gonioscopic contact lens mounted into one side by means of a watertight seal. The laser was used to produce lesions in the trabecular meshwork on either side of each specimen. The energy levels delivered ranged from 0.5 to 7.0 mJ, and convergence angles of 10 degrees and 18 degrees were employed. The energy levels required to produce discrete lesions into the canal of Schlemm without perforating the underlying sclera were 3.0-5.0 mJ at the 10 degrees convergence angle and 4.0-6.0 mJ at the 18 degrees convergence angle setting. It is recommended that such data be determined for each type of laser prior to attempting short-pulsed laser internal trabeculotomy in patients with glaucoma.

Full text

PDF
782

Images in this article

784Image
on p.784

Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. Aron-Rosa D. S., Aron J. J., Cohn H. C. Use of a pulsed picosecond Nd: YAG laser in 6,664 cases. J Am Intraocul Implant Soc. 1984 Winter;10(1):35–39. doi: 10.1016/s0146-2776(84)80074-9. [DOI] [PubMed] [Google Scholar]
  2. Belcher C. D., 3rd, Mainster M. A., Buzney S. M. Current status of neodymium: YAG laser photodisruptors in ophthalmology: Part II. Ann Ophthalmol. 1983 Dec;15(12):1097–1099. [PubMed] [Google Scholar]
  3. Cairns J. E. Trabeculectomy. Preliminary report of a new method. Am J Ophthalmol. 1968 Oct;66(4):673–679. [PubMed] [Google Scholar]
  4. Epstein D. L., Melamed S., Puliafto C. A., Steinert R. F. Neodymium: YAG laser trabeculopuncture in open-angle glaucoma. Ophthalmology. 1985 Jul;92(7):931–937. doi: 10.1016/s0161-6420(85)33932-5. [DOI] [PubMed] [Google Scholar]
  5. Fankhauser F., Lörtscher H., van der Zypen E. Clinical studies on high and low power laser radiation upon some structures of the anterior and posterior segments of the eye. Experiences in the treatment of some pathological conditions of the anterior and posterior segments of the human eye by means of a Nd:YAG laser, driven at various power levels. Int Ophthalmol. 1982 May;5(1):15–32. doi: 10.1007/BF00129992. [DOI] [PubMed] [Google Scholar]
  6. Goldschmidt C. R., Ticho U. Theoretical approach to laser trabeculotomy. Med Phys. 1978 Mar-Apr;5(2):92–99. doi: 10.1118/1.594415. [DOI] [PubMed] [Google Scholar]
  7. Krasnov M. M. Q-switched laser goniopuncture. Arch Ophthalmol. 1974 Jul;92(1):37–41. doi: 10.1001/archopht.1974.01010010041010. [DOI] [PubMed] [Google Scholar]
  8. March W. F., Gherezghiher T., Koss M., Nordquist R. Ultrastructural and pharmacologic studies on laser-induced glaucoma in primates and rabbits. Lasers Surg Med. 1984;4(4):329–335. doi: 10.1002/lsm.1900040405. [DOI] [PubMed] [Google Scholar]
  9. Melamed S., Pei J., Puliafito C. A., Epstein D. L. Q-switched neodymium-YAG laser trabeculopuncture in monkeys. Arch Ophthalmol. 1985 Jan;103(1):129–133. doi: 10.1001/archopht.1985.01050010135037. [DOI] [PubMed] [Google Scholar]
  10. Robin A. L., Pollack I. P. Q-switched neodymium-YAG laser angle surgery in open-angle glaucoma. Arch Ophthalmol. 1985 Jun;103(6):793–795. doi: 10.1001/archopht.1985.01050060053023. [DOI] [PubMed] [Google Scholar]
  11. Robin A. L., Pollack I. P. The Q-switched ruby laser in glaucoma. Ophthalmology. 1984 Apr;91(4):366–372. doi: 10.1016/s0161-6420(84)34278-6. [DOI] [PubMed] [Google Scholar]
  12. SMITH R. A new technique for opening the canal of Schlemm. Preliminary report. Br J Ophthalmol. 1960 Jun;44:370–373. doi: 10.1136/bjo.44.6.370. [DOI] [PMC free article] [PubMed] [Google Scholar]
  13. Schrems W., Glaab-Schrems E., Krieglstein G. K., Leydhecker W. Zur Wirkung der Neodym-YAG-Laserbehandlung beim Offenwinkel-Glaukom. Fortschr Ophthalmol. 1985;82(4):382–384. [PubMed] [Google Scholar]
  14. Ticho U., Cadet J. C., Mahler J., Sekeles E., Bruchim A. Argon laser trabeculotomies in primates: evaluation by histological and perfusion studies. Invest Ophthalmol Vis Sci. 1978 Jul;17(7):667–674. [PubMed] [Google Scholar]
  15. Venkatesh S., Guthrie S., Foulds W. S., Lee W. R., Cruickshank F. R., Bailey R. T. In vitro studies with a pulsed neodymium/YAG laser. Br J Ophthalmol. 1985 Feb;69(2):86–91. doi: 10.1136/bjo.69.2.86. [DOI] [PMC free article] [PubMed] [Google Scholar]
  16. Venkatesh S., Lee W. R., Guthrie S., Cruickshank F. R., Foulds W. S., Quigley R. J., Bailey R. T. An in-vitro morphological study of Q-switched neodymium/YAG laser trabeculotomy. Br J Ophthalmol. 1986 Feb;70(2):89–96. doi: 10.1136/bjo.70.2.89. [DOI] [PMC free article] [PubMed] [Google Scholar]
  17. Watson P. G. Surgery of the glaucomas. Br J Ophthalmol. 1972 Mar;56(3):299–306. doi: 10.1136/bjo.56.3.299. [DOI] [PMC free article] [PubMed] [Google Scholar]
  18. Wise J. B., Witter S. L. Argon laser therapy for open-angle glaucoma. A pilot study. Arch Ophthalmol. 1979 Feb;97(2):319–322. doi: 10.1001/archopht.1979.01020010165017. [DOI] [PubMed] [Google Scholar]
  19. van der Zypen E., Bebie H., Fankhauser F. Morphological studies about the efficiency of laser beams upon the structures of the angle of the anterior chamber. Facts and concepts related to the treatment of the chronic simple glaucoma. Int Ophthalmol. 1979 Feb;1(2):109–122. doi: 10.1007/BF00154198. [DOI] [PubMed] [Google Scholar]

Articles from The British Journal of Ophthalmology are provided here courtesy of BMJ Publishing Group

RESOURCES