Abstract
A 52-year-old woman was found to have a small juxtapapillary pigmented lesion in the choroid of the left eye. This lesion remained clinically stationary for one year, but subsequent growth prompted enucleation of the eye. The tumour was diagnosed histologically as a choroidal malignant melanoma of mixed cell type. Approximately 52 months later the patient developed proptosis of the contralateral (right) eye. Orbital ultrasonography showed a large mass in the right orbit, which was confirmed by needle biopsy to be a melanoma. In addition the patient was found to have metastatic melanoma to the choroid, right lower eyelid area, and liver. The development of simultaneous orbital, choroidal, and eyelid metastases from a contralateral choroidal melanoma is of ophthalmic interest and appears to be unique.
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- COWIE J. W., FOSTER J., HARRIMAN D. S., HENDERSON W. Choroidal sarcoma with metastasis in the opposite orbit. Br J Ophthalmol. 1957 Jan;41(1):42–47. doi: 10.1136/bjo.41.1.42. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Font R. L., Naumann G., Zimmerman L. E. Primary malignant melanoma of the skin metastatic to the eye and orbit. Report of ten cases and review of the literature. Am J Ophthalmol. 1967 Apr;63(4):738–754. doi: 10.1016/0002-9394(67)91300-1. [DOI] [PubMed] [Google Scholar]
- PHILPS S. Choroidal sarcoma with metastasis in the opposite orbit. Br J Ophthalmol. 1949 Dec;33(12):732-9, illust. doi: 10.1136/bjo.33.12.732. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Shields J. A., Bakewell B., Augsburger J. J., Flanagan J. C. Classification and incidence of space-occupying lesions of the orbit. A survey of 645 biopsies. Arch Ophthalmol. 1984 Nov;102(11):1606–1611. doi: 10.1001/archopht.1984.01040031296011. [DOI] [PubMed] [Google Scholar]
- de Bustros S., Augsburger J. J., Shields J. A., Shakin E. P., Pryor C. C., 2nd Intraocular metastases from cutaneous malignant melanoma. Arch Ophthalmol. 1985 Jul;103(7):937–940. doi: 10.1001/archopht.1985.01050070063031. [DOI] [PubMed] [Google Scholar]