Skip to main content
The British Journal of Ophthalmology logoLink to The British Journal of Ophthalmology
. 1989 May;73(5):388–393. doi: 10.1136/bjo.73.5.388

Primary malignant melanoma of the orbit arising in a cellular blue naevus.

K U Löffler 1, H Witschel 1
PMCID: PMC1041749  PMID: 2730864

Abstract

Primary malignant melanoma of the orbit is a rare clinical entity. We report the clinical course and present the light and electron microscopic findings in a case arising in a cellular blue naevus. While most orbital melanomas are associated with a naevus of Ota, there was no clinically visible abnormal pigmentation in our patient. The possible origin of the tumour cell and its ultrastructural features are discussed.

Full text

PDF
388

Images in this article

Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. Coppeto J. R., Jaffe R., Gillies C. G. Primary orbital melanoma. Arch Ophthalmol. 1978 Dec;96(12):2255–2258. doi: 10.1001/archopht.1978.03910060551018. [DOI] [PubMed] [Google Scholar]
  2. Drews R. C. Primary malignant melanoma of the orbit in a Negro. Arch Ophthalmol. 1975 May;93(5):335–336. doi: 10.1001/archopht.1975.01010020347004. [DOI] [PubMed] [Google Scholar]
  3. Dutton J. J., Anderson R. L., Schelper R. L., Purcell J. J., Tse D. T. Orbital malignant melanoma and oculodermal melanocytosis: report of two cases and review of the literature. Ophthalmology. 1984 May;91(5):497–507. doi: 10.1016/s0161-6420(84)34261-0. [DOI] [PubMed] [Google Scholar]
  4. Hagler W. S., Brown C. C. Malignant melanoma of the orbit arising in a nevus of Ota. Trans Am Acad Ophthalmol Otolaryngol. 1966 Sep-Oct;70(5):817–822. [PubMed] [Google Scholar]
  5. Jakobiec F. A., Ellsworth R., Tannenbaum M. Primary orbital melanoma. Am J Ophthalmol. 1974 Jul;78(1):24–39. doi: 10.1016/0002-9394(74)90005-1. [DOI] [PubMed] [Google Scholar]
  6. Jakobiec F. A. The ultrastructure of conjunctival melanocytic tumors. Trans Am Ophthalmol Soc. 1984;82:599–752. [PMC free article] [PubMed] [Google Scholar]
  7. Jay B. Malignant melanoma of the orbit in a case of oculodermal melanosis. (Naevus of Ota). Br J Ophthalmol. 1965 Jul;49(7):359–363. doi: 10.1136/bjo.49.7.359. [DOI] [PMC free article] [PubMed] [Google Scholar]
  8. Merkow L. P., Burt R. C., Hayeslip D. W., Newton F. J., Slifkin M., Pardo M. A cellular and malignant blue nevus: a light and electron microscopic study. Cancer. 1969 Nov;24(5):888–896. doi: 10.1002/1097-0142(196911)24:5<888::aid-cncr2820240505>3.0.co;2-8. [DOI] [PubMed] [Google Scholar]
  9. Shields J. A., Elder D., Arbizo V., Hedges T., Augsburger J. J. Orbital involvement with desmoplastic melanoma. Br J Ophthalmol. 1987 Apr;71(4):279–284. doi: 10.1136/bjo.71.4.279. [DOI] [PMC free article] [PubMed] [Google Scholar]
  10. Silverberg G. D., Kadin M. E., Dorfman R. F., Hanbery J. W., Prolo D. J. Invasion of the brain by a cellular blue nevus of the scalp. A case report with light and electron microscopic studies. Cancer. 1971 Feb;27(2):349–355. doi: 10.1002/1097-0142(197102)27:2<349::aid-cncr2820270216>3.0.co;2-r. [DOI] [PubMed] [Google Scholar]
  11. Wolter J. R., Bryson J. M., Blackhurst R. T. Primary orbital melanoma. Eye Ear Nose Throat Mon. 1966 Aug;45(8):64–passim. [PubMed] [Google Scholar]

Articles from The British Journal of Ophthalmology are provided here courtesy of BMJ Publishing Group

RESOURCES