Skip to main content
The British Journal of Ophthalmology logoLink to The British Journal of Ophthalmology
. 1989 Jun;73(6):468–469. doi: 10.1136/bjo.73.6.468

Adverse effect of intraoperative phenylephrine 10%: case report.

Y K Lai 1
PMCID: PMC1041770  PMID: 2751981

Abstract

The case is reported of a patient who suffered severe acute hypertension, cardiac arrhythmia, and myocardial infarction probably as a direct effect of phenylephrine overdose. Instillation of the drops during surgery probably enhanced the systemic absorption of a significant amount of the drug. Therefore it should be used during surgery with caution, especially in elderly patients and those with cardiovascular disease.

Full text

PDF
468

Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. Fraunfelder F. T., Scafidi A. F. Possible adverse effects from topical ocular 10% phenylephrine. Am J Ophthalmol. 1978 Apr;85(4):447–453. doi: 10.1016/s0002-9394(14)75239-0. [DOI] [PubMed] [Google Scholar]
  2. HAVENER W. H., HENDERSON J. W., MCREYNOLDS W. U. Hazards of the use of sympathomimetic drugs in ophthalmology. AMA Arch Ophthalmol. 1956 Aug;56(2):176–179. doi: 10.1001/archopht.1956.00930040184003. [DOI] [PubMed] [Google Scholar]

Articles from The British Journal of Ophthalmology are provided here courtesy of BMJ Publishing Group

RESOURCES