Abstract
There are conflicting reports on the value of cyclocryotherapy in the management of glaucoma. This retrospective study was carried out to assess the efficacy and complication rate of this procedure. The case notes of all patients undergoing cyclocryotherapy at a single centre over a 10-year period were reviewed. Case records were available for 68 eyes of 64 people. Thirty-eight eyes had neovascular glaucoma, nine had aphakic glaucoma, nine had angle closure glaucoma, three had primary open angle glaucoma, and nine had secondary open angle glaucoma. The mean follow-up periods for these groups varied from 2.0-6.3 years. The mean reduction in intraocular pressure following treatment varied from 7.9 mm Hg in the secondary open angle glaucoma group to 24.3 mm Hg in those with angle closure glaucoma. Pressure was controlled in 29.4% overall, ranging from 66.7% in the angle closure and primary open angle groups to 0% in the secondary open angle group. Of the painful eyes 71% were rendered comfortable, indicating that pain relief from cyclocryotherapy is not due solely to pressure control. 30% of the patients lost their vision following the procedure, phthisis occurred in 11.8% and four eyes (5.9%) went on to enucleation. Our results indicate that cyclocryotherapy affords good pain relief, without good pressure control, in various types of glaucoma. While there is an apparent high complication rate, visual loss and phthisis cannot be ascribed directly to the procedure, since these are eyes with a poor prognosis.
Full text
PDF


Selected References
These references are in PubMed. This may not be the complete list of references from this article.
- Allen R. C., Bellows A. R., Hutchinson B. T., Murphy S. D. Filtration surgery in the treatment of neovascular glaucoma. Ophthalmology. 1982 Oct;89(10):1181–1187. doi: 10.1016/s0161-6420(82)34672-2. [DOI] [PubMed] [Google Scholar]
- BIETTI G. Surgical intervention on the ciliary body; new trends for the relief of glaucoma. J Am Med Assoc. 1950 Mar 25;142(12):889–897. doi: 10.1001/jama.1950.02910300027006. [DOI] [PubMed] [Google Scholar]
- Bellows A. R., Grant W. M. Cyclocryotherapy in advanced inadequately controlled glaucoma. Am J Ophthalmol. 1973 Apr;75(4):679–684. doi: 10.1016/0002-9394(73)90820-9. [DOI] [PubMed] [Google Scholar]
- Brindley G., Shields M. B. Value and limitations of cyclocryotherapy. Graefes Arch Clin Exp Ophthalmol. 1986;224(6):545–548. doi: 10.1007/BF02154743. [DOI] [PubMed] [Google Scholar]
- Caprioli J., Strang S. L., Spaeth G. L., Poryzees E. H. Cyclocryotherapy in the treatment of advanced glaucoma. Ophthalmology. 1985 Jul;92(7):947–954. doi: 10.1016/s0161-6420(85)33951-9. [DOI] [PubMed] [Google Scholar]
- Feibel R. M., Bigger J. F. Rubeosis iridis and neovascular glaucoma. Evaluation of cyclocryotherapy. Am J Ophthalmol. 1972 Nov;74(5):862–867. doi: 10.1016/0002-9394(72)91206-8. [DOI] [PubMed] [Google Scholar]
- Higginbotham E. J., Lee D. A., Bartels S. P., Richardson T., Miller M. Effects of cyclocryotherapy on aqueous humor dynamics in cats. Arch Ophthalmol. 1988 Mar;106(3):396–403. doi: 10.1001/archopht.1988.01060130422034. [DOI] [PubMed] [Google Scholar]
- Krupin T., Mitchell K. B., Becker B. Cyclocryotherapy in neovascular glaucoma. Am J Ophthalmol. 1978 Jul;86(1):24–26. doi: 10.1016/0002-9394(78)90008-9. [DOI] [PubMed] [Google Scholar]
- Parrish R., Herschler J. Eyes with end-stage neovascular glaucoma. Natural history following successful modified filtering operation. Arch Ophthalmol. 1983 May;101(5):745–746. doi: 10.1001/archopht.1983.01040010745008. [DOI] [PubMed] [Google Scholar]
- Prost M. Anatomy of the ciliary body and cyclocryotherapy. Ophthalmologica. 1984;188(1):9–13. doi: 10.1159/000309338. [DOI] [PubMed] [Google Scholar]
- Prost M. Cyclocryotherapy for glaucoma. Evaluation of techniques. Surv Ophthalmol. 1983 Sep-Oct;28(2):93–100. doi: 10.1016/0039-6257(83)90077-2. [DOI] [PubMed] [Google Scholar]
