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. 1990 Oct;74(10):629–630. doi: 10.1136/bjo.74.10.629

A case of cerebrotendinous xanthomatosis. II: The sterol content of a cataractous lens.

P McKenna 1, S J Morgan 1, R C Bosanquet 1, M F Laker 1
PMCID: PMC1042235  PMID: 2285688

Abstract

The cholestanol content of a cataractous lens nucleus from a patient with cerebrotendinous xanthomatosis (CTX) was quantified by gas chromatography-mass spectrometry and found to be 0.27 micrograms per mg freeze-dried lens tissue. The cholestanol-cholesterol ratio of 1.7% in the lens nucleus was similar to that in the serum of the CTX patient. The cholestanol content and cholestanol-cholesterol ratio in the CTX lens were approximately four-fold and six-fold greater respectively than the mean levels found in three senile cataractous lens nuclei analysed simultaneously for comparative purposes.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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