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. 1991 Mar;75(3):160–162. doi: 10.1136/bjo.75.3.160

Effect of partial cryoablation on retinopathy of prematurity.

I Nissenkorn 1, R Axer-Siegel 1, I Kremer 1, I Ben-Sira 1
PMCID: PMC1042297  PMID: 2012783

Abstract

Cryotherapy has been shown to be an effective treatment for retinopathy of prematurity stage 3. It is said to reduce the unfavourable outcome of the disease by 50%. The accepted method of therapy includes ablation of the whole avascular retina from the ridge to the ora serrata. This is achieved by two to three rows of cryoapplications. When 360 degrees cryo treatment is performed, it requires 52 cryo applications. We present our method of cryotherapy which involves only one row of cryoapplications in the avascular retina anterior to the fibrovascular ridge. An average of 25-30 cryoapplications was required for a 360 degrees treatment. The anatomical results in 23 babies are presented. Complete regression of active retinopathy was found in all.

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Selected References

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  1. ASHTON N., WARD B., SERPELL G. Effect of oxygen on developing retinal vessels with particular reference to the problem of retrolental fibroplasia. Br J Ophthalmol. 1954 Jul;38(7):397–432. doi: 10.1136/bjo.38.7.397. [DOI] [PMC free article] [PubMed] [Google Scholar]
  2. ASHTON N., WARD B., SERPELL G. Role of oxygen in the genesis of retrolental fibroplasia; a preliminary report. Br J Ophthalmol. 1953 Sep;37(9):513–520. doi: 10.1136/bjo.37.9.513. [DOI] [PMC free article] [PubMed] [Google Scholar]
  3. Ben Sira I., Nissenkorn I., Kremer I. Retinopathy of prematurity. Surv Ophthalmol. 1988 Jul-Aug;33(1):1–16. doi: 10.1016/0039-6257(88)90068-9. [DOI] [PubMed] [Google Scholar]
  4. Ben-Sira I., Nissenkorn I., Grunwald E., Yassur Y. Treatment of acute retrolental fibroplasia by cryopexy. Br J Ophthalmol. 1980 Oct;64(10):758–762. doi: 10.1136/bjo.64.10.758. [DOI] [PMC free article] [PubMed] [Google Scholar]
  5. Foos R. Y. Acute retrolental fibroplasia. Albrecht Von Graefes Arch Klin Exp Ophthalmol. 1975;195(2):87–100. doi: 10.1007/BF00417112. [DOI] [PubMed] [Google Scholar]
  6. Greven C. M., Tasman W. Rhegmatogenous retinal detachment following cryotherapy in retinopathy of prematurity. Arch Ophthalmol. 1989 Jul;107(7):1017–1018. doi: 10.1001/archopht.1989.01070020079034. [DOI] [PubMed] [Google Scholar]
  7. Harris G. S. Retinopathy of prematurity and retinal detachment. Can J Ophthalmol. 1976 Jan;11(1):21–25. [PubMed] [Google Scholar]
  8. Hindle N. W., Leyton J. Prevention of cicatricial retrolental fibroplasia by cryotherapy. Can J Ophthalmol. 1978 Oct;13(4):277–282. [PubMed] [Google Scholar]
  9. Keith C. G. Visual outcome and effect of treatment in stage III developing retrolental fibroplasia. Br J Ophthalmol. 1982 Jul;66(7):446–449. doi: 10.1136/bjo.66.7.446. [DOI] [PMC free article] [PubMed] [Google Scholar]
  10. Kingham J. D. Acute retrolental fibroplasia. II. Treatment by cryosurgery. Arch Ophthalmol. 1978 Nov;96(11):2049–2053. doi: 10.1001/archopht.1978.03910060437008. [DOI] [PubMed] [Google Scholar]
  11. Kretzer F. L., Mehta R. S., Johnson A. T., Hunter D. G., Brown E. S., Hittner H. M. Vitamin E protects against retinopathy of prematurity through action on spindle cells. 1984 Jun 28-Jul 4Nature. 309(5971):793–795. doi: 10.1038/309793a0. [DOI] [PubMed] [Google Scholar]
  12. May D. R., Bergstrom T. J., Parmet A. J., Schwartz J. G. Treatment of neovascular glaucoma with transscleral panretinal cryotherapy. Ophthalmology. 1980 Nov;87(11):1106–1111. doi: 10.1016/s0161-6420(80)35122-1. [DOI] [PubMed] [Google Scholar]
  13. Mousel D. K. Cryotherapy for retinopathy of prematurity. A personal retrospective. Ophthalmology. 1985 Mar;92(3):375–378. doi: 10.1016/s0161-6420(85)34039-3. [DOI] [PubMed] [Google Scholar]
  14. Nissenkorn I., Kremer I., Ben Sira I., Cohen S., Garner A. A clinicopathological case of retinopathy of prematurity (ROP) treated by peripheral cryopexy. Br J Ophthalmol. 1984 Jan;68(1):36–41. doi: 10.1136/bjo.68.1.36. [DOI] [PMC free article] [PubMed] [Google Scholar]
  15. Nissenkorn I., Kremer I., Gilad E., Cohen S., Ben-Sira I. 'Rush' type retinopathy of prematurity: report of three cases. Br J Ophthalmol. 1987 Jul;71(7):559–562. doi: 10.1136/bjo.71.7.559. [DOI] [PMC free article] [PubMed] [Google Scholar]
  16. PATZ A., EASTHAM A., HIGGINBOTHAM D. H., KLEH T. Oxygen studies in retrolental fibroplasia. II. The production of the microscopic changes of retrolental fibroplasia in experimental animals. Am J Ophthalmol. 1953 Nov;36(11):1511–1522. [PubMed] [Google Scholar]
  17. Payne J. W., Patz A. Treatment of acute proliferative retrolental fibroplasia. Trans Am Acad Ophthalmol Otolaryngol. 1972 Sep-Oct;76(5):1234–1246. [PubMed] [Google Scholar]
  18. Tasman W., Brown G. C., Schaffer D. B., Quinn G., Naidoff M., Benson W. E., Diamond G. Cryotherapy for active retinopathy of prematurity. Ophthalmology. 1986 May;93(5):580–585. doi: 10.1016/s0161-6420(86)33680-7. [DOI] [PubMed] [Google Scholar]
  19. Tasman W., Magargal L. E., Augsburger J. J. Effects of argon laser photocoagulation on rubeosis iridis and angle neovascularization. Ophthalmology. 1980 May;87(5):400–402. doi: 10.1016/s0161-6420(80)35225-1. [DOI] [PubMed] [Google Scholar]
  20. Tasman W. Management of retinopathy of prematurity. Ophthalmology. 1985 Aug;92(8):995–999. doi: 10.1016/s0161-6420(85)33918-0. [DOI] [PubMed] [Google Scholar]
  21. Taylor C. M., Weiss J. B., Kissun R. D., Garner A. Effect of oxygen tension on the quantities of procollagenase-activating angiogenic factor present in the developing kitten retina. Br J Ophthalmol. 1986 Mar;70(3):162–165. doi: 10.1136/bjo.70.3.162. [DOI] [PMC free article] [PubMed] [Google Scholar]

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