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. 1991 Nov;75(11):652–655. doi: 10.1136/bjo.75.11.652

Postural change of intraocular and blood pressures in ocular hypertension and low tension glaucoma.

S Yamabayashi 1, R N Aguilar 1, M Hosoda 1, S Tsukahara 1
PMCID: PMC1042519  PMID: 1751457

Abstract

The effect of body position on the intraocular and blood pressures of normal volunteers and of patients with ocular hypertension and low tension glaucoma was studied. Changing from the sitting to the supine position increased the intraocular pressure by an average of 4.4 (SD 2.0) mm Hg in the control group, 4.0 (SD 2.0) mm Hg in the ocular hypertension group, and 4.1 (SD 1.8 mm Hg) in the low-tension glaucoma group. After 30 minutes in the supine position the intraocular pressure in normal volunteers and patients with low tension glaucoma remained stable. In contrast patients with ocular hypertension showed a further significant increase in intraocular pressure of 1.6 (SD 2.8) mm Hg (p = 0.004). This was accompanied by an equally significant decrease in blood pressure (p less than 0.001). We believe that these are manifestations of different mechanism of intraocular pressure regulation between these groups.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. Anderson D. R., Grant W. M. The influence of position on intraocular pressure. Invest Ophthalmol. 1973 Mar;12(3):204–212. [PubMed] [Google Scholar]
  2. Clark C. V., Mapstone R. Anterior segment autonomic dysfunction in ocular hypertension. Doc Ophthalmol. 1986;64(2):201–207. doi: 10.1007/BF00159994. [DOI] [PubMed] [Google Scholar]
  3. Clark C. V., Mapstone R. Autonomic neuropathy in ocular hypertension. Lancet. 1985 Jul 27;2(8448):185–187. doi: 10.1016/s0140-6736(85)91500-4. [DOI] [PubMed] [Google Scholar]
  4. Clark C. V., Mapstone R. Parasympathetic denervation hypersensitivity of the iris in ocular hypertension. Invest Ophthalmol Vis Sci. 1987 Oct;28(10):1732–1735. [PubMed] [Google Scholar]
  5. GALIN M. A., McIVOR J. W., MAGRUDER G. B. Influence of position on intraocular pressure. Am J Ophthalmol. 1963 Apr;55:720–723. [PubMed] [Google Scholar]
  6. Geijer C., Bill A. Effects of raised intraocular pressure on retinal, prelaminar, laminar, and retrolaminar optic nerve blood flow in monkeys. Invest Ophthalmol Vis Sci. 1979 Oct;18(10):1030–1042. [PubMed] [Google Scholar]
  7. Jain M. R., Marmion V. J. Rapid pneumatic and Mackey-Marg applanation tonometry to evaluate the postural effect on intraocular pressure. Br J Ophthalmol. 1976 Oct;60(10):687–693. doi: 10.1136/bjo.60.10.687. [DOI] [PMC free article] [PubMed] [Google Scholar]
  8. Krieglstein G. K., Waller W. K., Leydhecker W. The vascular basis of the positional influence of the intraocular pressure. Albrecht Von Graefes Arch Klin Exp Ophthalmol. 1978 May 2;206(2):99–106. doi: 10.1007/BF00414618. [DOI] [PubMed] [Google Scholar]
  9. Leighton D. A., Phillips C. I. Systemic blood pressure in open-angle glaucoma, low tension glaucoma, and the normal eye. Br J Ophthalmol. 1972 Jun;56(6):447–453. doi: 10.1136/bjo.56.6.447. [DOI] [PMC free article] [PubMed] [Google Scholar]
  10. Leonard T. J., Kerr Muir M. G., Kirkby G. R., Hitchings R. A. Ocular hypertension and posture. Br J Ophthalmol. 1983 Jun;67(6):362–366. doi: 10.1136/bjo.67.6.362. [DOI] [PMC free article] [PubMed] [Google Scholar]
  11. Linder B. J., Trick G. L., Wolf M. L. Altering body position affects intraocular pressure and visual function. Invest Ophthalmol Vis Sci. 1988 Oct;29(10):1492–1497. [PubMed] [Google Scholar]
  12. Shibata T., Kondo K., Mishima H. [The effect of body position on intraocular pressure in normal and glaucomatous eyes--a comparative study with pneumatonograph]. Nippon Ganka Gakkai Zasshi. 1985 May;89(5):696–701. [PubMed] [Google Scholar]
  13. Trew D. R., Smith S. E. Postural studies in pulsatile ocular blood flow: I. Ocular hypertension and normotension. Br J Ophthalmol. 1991 Feb;75(2):66–70. doi: 10.1136/bjo.75.2.66. [DOI] [PMC free article] [PubMed] [Google Scholar]
  14. Tsukahara S., Sasaki T. Postural change of IOP in normal persons and in patients with primary wide open-angle glaucoma and low-tension glaucoma. Br J Ophthalmol. 1984 Jun;68(6):389–392. doi: 10.1136/bjo.68.6.389. [DOI] [PMC free article] [PubMed] [Google Scholar]
  15. Weber A. K., Price J. Pressure differential of intraocular pressure measured between supine and sitting position. Ann Ophthalmol. 1981 Mar;13(3):323–326. [PubMed] [Google Scholar]
  16. Williams B. I., Peart W. S., Letley E. Abnormal intraocular pressure control in systemic hypertension and diabetic mellitus. Br J Ophthalmol. 1980 Nov;64(11):845–851. doi: 10.1136/bjo.64.11.845. [DOI] [PMC free article] [PubMed] [Google Scholar]
  17. Wüthrich U. W. Postural change and intraocular pressure in glaucomatous eyes. Br J Ophthalmol. 1976 Feb;60(2):111–114. doi: 10.1136/bjo.60.2.111. [DOI] [PMC free article] [PubMed] [Google Scholar]

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