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. 1991 Dec;75(12):715–717. doi: 10.1136/bjo.75.12.715

Treatment of juxtapapillary melanomas.

P K Lommatzsch 1, R Lommatzsch 1
PMCID: PMC1042548  PMID: 1768658

Abstract

Thirty nine patients suffering from juxtapapillary choroidal melanoma were treated with Ru-106/Rh-106 beta-ray plaques. The tumoricidal dose was 100 Gy at the apex of the tumour within 7-14 days. Additional photocoagulation was performed in 12 eyes. The irradiated eyes of three patients had to be enucleated, seven patients died, five of them (12.8%) from metastases. Thirty two (82%) patients are alive and 29 (74%) have a seeing eye. From the whole series 20 (51%) developed flat scars and 11 (29%) patients retained a visual acuity of 0.5-1.0. Radiogenic late complications with damage to the optic nerve and macula were the main causes of visual deterioration.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. Foulds W. S. Experience of local excision of uveal melanomas. Trans Ophthalmol Soc U K. 1977 Sep;97(3):412–415. [PubMed] [Google Scholar]
  2. Gragoudas E. S., Goitein M., Verhey L., Munzenreider J., Suit H. D., Koehler A. Proton beam irradiation. An alternative to enucleation for intraocular melanomas. Ophthalmology. 1980 Jun;87(6):571–581. doi: 10.1016/s0161-6420(80)35212-3. [DOI] [PubMed] [Google Scholar]
  3. Lommatzsch P. K. Results after beta-irradiation (106Ru/106Rh) of choroidal melanomas: 20 years' experience. Br J Ophthalmol. 1986 Nov;70(11):844–851. doi: 10.1136/bjo.70.11.844. [DOI] [PMC free article] [PubMed] [Google Scholar]
  4. MacFaul P. A. Local radiotherapy in the treatment of malignant melanoma of the choroid. Trans Ophthalmol Soc U K. 1977 Sep;97(3):421–427. [PubMed] [Google Scholar]
  5. Packer S., Rotman M., Fairchild R. G., Albert D. M., Atkins H. L., Chan B. Irradiation of choroidal melanoma with iodine 125 ophthalmic plaque. Arch Ophthalmol. 1980 Aug;98(8):1453–1457. doi: 10.1001/archopht.1980.01020040305019. [DOI] [PubMed] [Google Scholar]
  6. Seddon J. M., Gragoudas E. S., Egan K. M., Glynn R. J., Munzenrider J. E., Austin-Seymour M., Goitein M., Verhey L., Urie M., Koehler A. Uveal melanomas near the optic disc or fovea. Visual results after proton beam irradiation. Ophthalmology. 1987 Apr;94(4):354–361. doi: 10.1016/s0161-6420(87)33439-6. [DOI] [PubMed] [Google Scholar]

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