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. 1980 Dec;64(12):926–932. doi: 10.1136/bjo.64.12.926

Study of congenital nystagmus: optokinetic nystagmus.

R D Yee, R W Baloh, V Honrubia
PMCID: PMC1042576  PMID: 7448147

Abstract

A severe defect of optokinetic nystagmus (OKN) was found in 46 patients with congenital nystagmus. Abnormal patterns of OKN, such as superimposition of pendular oscillations on the optokinetic slow component and inversion of OKN, were observed. Optokinetic gain (eye movement velocity/drum velocity) was decreased compared to that in normal subjects, and optokinetic after-nystagmus, or transient persistence of OKN after cessation of visual stimulation, was absent. These findings suggest that there is a defect in the subcortical optokinetic system in congenital nystagmus. Optokinetic responses did not clearly differentiate patients who had ocular lesions that impair vision, such as ocular albinism and opacities of the ocular media, from patients who did not have such lesions. Similar abnormal patterns of OKN were found in both groups of patients, although optokinetic gain tended to be lower in patients with ocular lesions than in those without lesions.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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