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. 1977 Jan;61(1):62–64. doi: 10.1136/bjo.61.1.62

HLA antigens and uveitis.

S Ohno, S J Kimura, G R O'Connor, D H Char
PMCID: PMC1042875  PMID: 556942

Abstract

We have studied the antigen frequencies in a group of adult patients with acute and chronic iridocyclitis and chronic, cyclitis. In patients with iridocyclitis a statistically significant increased incidence of HLA-B27 was noted, even in those patients without joint or systemic disease. Patients with chronic iridocyclitis also were noted to have an increased incidence of B27; however, those patients with chronic cyclitis did not. On the basis of HLA-B27 studies there appears to be a fundamental difference between adult and juvenile iridocyclitis.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. Aho K., Ahvonen P., Lassus A., Sievers K., Tilikainen A. HL-A antigen 27 and reactive arthritis. Lancet. 1973 Jul 21;2(7821):157–157. doi: 10.1016/s0140-6736(73)93109-7. [DOI] [PubMed] [Google Scholar]
  2. Brewerton D. A., Caffrey M., Nicholls A., Walters D., James D. C. Acute anterior uveitis and HL-A 27. Lancet. 1973 Nov 3;302(7836):994–996. doi: 10.1016/s0140-6736(73)91090-8. [DOI] [PubMed] [Google Scholar]
  3. Brewerton D. A., Hart F. D., Nicholls A., Caffrey M., James D. C., Sturrock R. D. Ankylosing spondylitis and HL-A 27. Lancet. 1973 Apr 28;1(7809):904–907. doi: 10.1016/s0140-6736(73)91360-3. [DOI] [PubMed] [Google Scholar]
  4. Brewerton D. A., James D. C. The histocompatibility antigen (HL-A 27) and disease. Semin Arthritis Rheum. 1975 Feb;4(3):191–207. doi: 10.1016/0049-0172(75)90009-8. [DOI] [PubMed] [Google Scholar]
  5. Caffrey M. F., James D. C. Human lymphocyte antigen association in ankylosing spondylitis. Nature. 1973 Mar 9;242(5393):121–121. doi: 10.1038/242121a0. [DOI] [PubMed] [Google Scholar]
  6. Ehlers N., Kissmeyer-Nielsen F., Kjerbye K. E., Lamm L. U. Letter: HL-A27 in acute and chronic uveitis. Lancet. 1974 Jan 19;1(7847):99–99. doi: 10.1016/s0140-6736(74)92330-7. [DOI] [PubMed] [Google Scholar]
  7. Mapstone R., Woodrow J. C. Letter: Acute anterior uveitis and HL-A 27. Lancet. 1974 Apr;1(7859):681–682. doi: 10.1016/s0140-6736(74)93235-8. [DOI] [PubMed] [Google Scholar]
  8. OATES J. K., YOUNG A. C. Sacro-iliitis in Reiter's disease. Br Med J. 1959 Apr 18;1(5128):1013–1015. doi: 10.1136/bmj.1.5128.1013. [DOI] [PMC free article] [PubMed] [Google Scholar]
  9. Ohno S., Char D. H., Kimura S. J., O'Connor G. R. HLA antigens and antinuclear antibody titres in juvenile chronic iridocyclitis. Br J Ophthalmol. 1977 Jan;61(1):59–61. doi: 10.1136/bjo.61.1.59. [DOI] [PMC free article] [PubMed] [Google Scholar]
  10. Schlosstein L., Terasaki P. I., Bluestone R., Pearson C. M. High association of an HL-A antigen, W27, with ankylosing spondylitis. N Engl J Med. 1973 Apr 5;288(14):704–706. doi: 10.1056/NEJM197304052881403. [DOI] [PubMed] [Google Scholar]
  11. WRIGHT R., LUMSDEN K., LUNTZ M. H., SEVEL D., TRUELOVE S. C. ABNORMALITIES OF THE SACRO-ILIAC JOINTS AND UVEITIS IN ULCERATIVE COLITIS. Q J Med. 1965 Apr;34:229–236. [PubMed] [Google Scholar]
  12. Woodrow J. C. HL-A 27 and Reiter's syndrome. Lancet. 1973 Sep 22;2(7830):671–672. doi: 10.1016/s0140-6736(73)92505-1. [DOI] [PubMed] [Google Scholar]
  13. Woodrow J. C., Mapstone R., Anderson J., Usher N. HL-A27 and anterior uveitis. Tissue Antigens. 1975 Sep;6(3):116–120. [PubMed] [Google Scholar]
  14. Zachariae H., Hjertshoj A., Kissmeyer-Nielsen F. Reiter's disease and HL-A 27. Lancet. 1973 Sep 8;2(7828):565–566. doi: 10.1016/s0140-6736(73)92385-4. [DOI] [PubMed] [Google Scholar]

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