Abstract
An open trial was carried out on 63 patients in London to assess the efficacy of 1% rifampicin eye ointment in comparison with 1% chloramphenicol eye ointment in the treatment of sexually transmitted TRIC infection of the eye. Patients included were selected on the basis of positive cultures for Chlamydia trachomatis. Three weeks' treatment with rifampicin eye ointment used 3 times daily was not sufficient to cure the disease, but a 6 or 7 week course gave 90% clinical and microbiological cure rate. Treatment with chloramphenicol eye ointment 3 times daily for 4 to 6 weeks failed to cure the disease.
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Selected References
These references are in PubMed. This may not be the complete list of references from this article.
- Becker Y., Asher Y., Himmel N., Zakay-Rones Z. Anti-trachoma activity of rifampicin and rifamycin SV derivatives. Nature. 1970 Jan 31;225(5231):454–455. doi: 10.1038/225454a0. [DOI] [PubMed] [Google Scholar]
- Becker Y. Rifampicin, an antitrachoma antibiotic. Isr J Med Sci. 1972 Aug-Sep;8(8):1110–1113. [PubMed] [Google Scholar]
- Darougar S., Jones B. R. Conjunctival swabbing for the isolation of TRIC agent (Chlamydia). Br J Ophthalmol. 1971 Sep;55(9):585–590. doi: 10.1136/bjo.55.9.585. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Dawson C. R., Hoshiwara I., Daghfous T., Messadi M., Vastine D. W., Schachter J. Topical tetracycline and rifampicin therapy of endemic trachoma in Tunisia. Am J Ophthalmol. 1975 May;79(5):803–811. doi: 10.1016/0002-9394(75)90740-0. [DOI] [PubMed] [Google Scholar]
- Dawson C. R., Jones B. R., Darougar S. Blinding and non-blinding trachoma: assessment of intensity of upper tarsal inflammatory disease and disabling lesions. Bull World Health Organ. 1975;52(3):279–282. [PMC free article] [PubMed] [Google Scholar]