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. 1979 Mar;63(3):165–168. doi: 10.1136/bjo.63.3.165

Primary cutaneous malignant melanoma metastatic to the iris.

L W Hirst, J Reich, J E Galbraith
PMCID: PMC1043433  PMID: 435426

Abstract

We describe a case of cutaneous malignant melanoma metastatic to the iris as the first presenting sign of metastases 10 years after excision of the primary tumour. The histology of the excised iris metastases and the primary skin melanoma are compared. Progressive intracranial metastatic growth did not correlate with the observed regression of the residual intraocular melanoma cells during cyclical cytotoxic therapy.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. Albert D. M., Zimmermann A. W., Jr, Zeidman I. Tumor metastasis to the eye. 3. The fate of circulating tumor cells to the eye. Am J Ophthalmol. 1967 Apr;63(4):733–738. doi: 10.1016/0002-9394(67)91299-8. [DOI] [PubMed] [Google Scholar]
  2. COVELL L. L., MARKIEWITZ H. H. The choroid as site of prime manifestation of systemic involvement in skin melanoma. Report of a case. Am J Ophthalmol. 1961 Jun;51:1296–1303. [PubMed] [Google Scholar]
  3. DASGUPTA T., BRASFIELD R. METASTATIC MELANOMA. A CLINICOPATHOLOGICAL STUDY. Cancer. 1964 Oct;17:1323–1339. doi: 10.1002/1097-0142(196410)17:10<1323::aid-cncr2820171015>3.0.co;2-n. [DOI] [PubMed] [Google Scholar]
  4. Ferry A. P., Font R. L. Carcinoma metastatic to the eye and orbit. I. A clinicopathologic study of 227 cases. Arch Ophthalmol. 1974 Oct;92(4):276–286. doi: 10.1001/archopht.1974.01010010286003. [DOI] [PubMed] [Google Scholar]
  5. Ferry A. P. Primary malignant melanoma of the skin metastatic to the eye. Am J Ophthalmol. 1972 Jul;74(1):12–19. doi: 10.1016/0002-9394(72)91118-x. [DOI] [PubMed] [Google Scholar]
  6. Fishman M. L., Tomaszewski M. M., Kuabara T. Malignant melanoma of the skin metastatic to the eye. Frequency in autopsy series. Arch Ophthalmol. 1976 Aug;94(8):1309–1311. doi: 10.1001/archopht.1976.03910040181010. [DOI] [PubMed] [Google Scholar]
  7. Font R. L., Naumann G., Zimmerman L. E. Primary malignant melanoma of the skin metastatic to the eye and orbit. Report of ten cases and review of the literature. Am J Ophthalmol. 1967 Apr;63(4):738–754. doi: 10.1016/0002-9394(67)91300-1. [DOI] [PubMed] [Google Scholar]
  8. Günther I. Augenmetastasen beim malignen Melanom der Haut. Klin Monbl Augenheilkd. 1973 Jun;162(6):821–823. [PubMed] [Google Scholar]
  9. JENSEN O. A. Choroid metastasis from a malignant melanoma of the skin. Acta Ophthalmol (Copenh) 1957;35(2):91–96. [PubMed] [Google Scholar]
  10. Kremlicka L., Roubková H., Cerná T. Prípad ocních metastáz primárního maligního melanomu kůze. Cesk Oftalmol. 1974 Mar;30(2):119–122. [PubMed] [Google Scholar]
  11. LIDDICOAT D. A., WOLTER J. R., WILKINSON W. C. Retinal metastasis of malignant melanoblastoma; a case report. Am J Ophthalmol. 1959 Aug;48(2):172–177. doi: 10.1016/0002-9394(59)91229-2. [DOI] [PubMed] [Google Scholar]
  12. Pennington D. G., Milton G. W. Cerebral metastasis from melanoma. Aust N Z J Surg. 1975 Nov;45(4):405–409. doi: 10.1111/j.1445-2197.1975.tb05783.x. [DOI] [PubMed] [Google Scholar]
  13. RIFFENBURGH R. S. Metastatic malignant melanoma to the retina. Arch Ophthalmol. 1961 Oct;66:487–489. doi: 10.1001/archopht.1961.00960010489009. [DOI] [PubMed] [Google Scholar]
  14. Szeps J., Patterson T. D. Metastatic malignant melanoma of ciliary body and choroid from a primary melanoma of skin. Can J Ophthalmol. 1969 Oct;4(4):394–399. [PubMed] [Google Scholar]

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