Abstract
The optic nerves and globes obtained from 6 anencephalics were studied histologically and compared to normal specimens obtained from 4 stillborn infants as well as 1 case of septo-optic dysplasia. Special emphasis was placed on examination of the optic nerve, and it was found that an average of 48 vessels per high-power field were seen posterior to the lamina cribrosa in anencephalics. In contrast, control globes had an average of 12 vessels per high-power field. This suggested that an increase in the vasculature of the hypoplastic optic nerve is a characteristic feature of anencephalics.
Full text
PDF
Images in this article
Selected References
These references are in PubMed. This may not be the complete list of references from this article.
- Addison D. J., Font R. L., Manschot W. A. Proliferative retinopathy in anencephalic babies. Am J Ophthalmol. 1972 Nov;74(5):967–976. doi: 10.1016/0002-9394(72)91220-2. [DOI] [PubMed] [Google Scholar]
- Andersen S. R., Bro-Rasmussen F., Tygstrup I. Anencephaly related to ocular development and malformation. Am J Ophthalmol. 1967 Sep;64(3 Suppl):559–566. doi: 10.1016/0002-9394(67)90560-0. [DOI] [PubMed] [Google Scholar]
- VOGEL F. S., McCLENAHAN J. L. Anomalies of major cerebral arteries associated with congenital malformations of the brain, with special reference to the pathogenesis of anencephaly. Am J Pathol. 1952 Jul-Aug;28(4):701–723. [PMC free article] [PubMed] [Google Scholar]