Table 3. Parameters for the neuron electrical properties.

* The membrane leak conductance in the spine is small since the spine membrane resistance is so high that is considered infinite (${\displaystyle >{10}^{6}M\mathrm{\Omega }}$) (Koch and Zador, 1993). The current thus mostly leaks axially through the neck cytoplasm. The dendrite leak conductance is also small in order to control the distance-dependent attenuation by the axial resistance term $g_{B\mathbf{}a\mathbf{}P}^{a\mathbf{}d\mathbf{}a\mathbf{}p\mathbf{}t}$ in Equation 4 and Equation 5. The table provides the parameters associated with these equations which were adjusted (see comparison with Reference value) to fit the dynamics seen in Golding et al., 2001 and Buchanan and Mellor, 2007 experiments as in Figure 9a and b.

Name	Value	Reference
Passive cable
Leak reversal potential	$E_{leak}=-70mV$	${\displaystyle 69mV}$ (Spigelman et al., 1996)
Membrane leak conductance per area (for spine and passive dendrite)	$g_{leak}=4\cdot {10}^{-6}nS/\mu m^2$	* see table legend (Koch and Zador, 1993)
Membrane leak conductance per area (only soma)	${\displaystyle g_{soma}=5.31\cdot {10}^{-3}nS/\mu m^2}$	${\displaystyle 3\cdot {10}^{-4}\text{ to }1.3\cdot {10}^{-3}nS/\mu m^2}$ (Fernandez and White, 2010)
Membrane capacitance per area	$C_m=6\cdot {10}^{-3}pF/\mu m^2$	$1\cdot {10}^{-2}pF/\mu m^2$  (Hines and Carnevale, 1997)
Axial resistivity of cytoplasm	$R_a=1\cdot {10}^{-2}G\mathrm{\Omega }\mu m$	$2\cdot {10}^{-3}G\mathrm{\Omega }\mu m$ (Golding et al., 2001)
Dendrite
Dendrite diameter	$D_{dend}=2\mu m$	same as Yi et al., 2017
Dendrite length	$L_{dend}=1400\mu m$	apical dendrites, 1200–1600 μm López Mendoza et al., 2018
Dendrite surface area	$A_{dend}=8.79\cdot {10}^3\mu m^2$	$\pi \cdot D_{dend}\cdot L_{dend}$
Dendrite volume	$Vo{l}_{dend}=4.4\cdot {10}^3\mu m^3$	$\pi \cdot {(D_{dend}/2)}^2\cdot L_{dend}$
Dendritic membrane capacitance	$C_{dend}=52.77pF$	$C_m\cdot A_{dend}$
Dendrite leak conductance	$g_L^{dend}=3.51\cdot {10}^{-2}nS$	$g_{leak}\cdot A_{dend}$
Dendrite axial conductance	$g_{diff}=50nS$	$R_a\cdot A_{dend}$
Soma
Soma diameter	$D_{soma}=30\mu m$	21 μm (Stuart et al., 2016) page 3
Soma area (sphere)	$A_{soma}=2.82\cdot {10}^3\mu m^2$	$(4\pi /3)\cdot {(D_{soma}/2)}^3$; $2.12\cdot {10}^3\mu m^2$  (Zhuravleva et al., 1997)
Soma membrane capacitance	$C_{soma}=16.96pF$	$C_m\cdot A_{soma}$
Soma leaking conductance	$g_L^{soma}=15nS$	$g_{soma}\cdot A_{soma}$ (Fernandez and White, 2010)
Dendritic spine
Spine head volume	$Vo{l}_{sp}=0.03\mu m^3$	Bartol et al., 2015
Spine head surface	$A_{sp}=4.66\cdot {10}^{-1}\mu m^2$	$4\pi \cdot {(3Vo{l}_{sp}/4\pi )}^{2/3}$
Spine membrane capacitance	$C_{sp}=2.8\cdot {10}^{-3}pF$	$C_m\cdot A_{sp}$
Spine head leak conductance	$g_L^{sp}=1.86\cdot {10}^{-6}nS$	$g_{leak}\cdot A_{sp}$
Dendritic spine neck
Spine neck diameter	$D_{neck}=0.1\mu m$	0.05–0.6 μm Harris et al., 1992
Neck length	$L_{neck}=0.2\mu m$	$0.7\pm 0.6\mu m$ (Adrian et al., 2017)
Neck cross-sectional area	$C{S}_{neck}=7.85\cdot {10}^{-3}\mu m^2$	$\pi \cdot {(D_{neck}/2)}^2$
Neck resistance	$g_{neck}=3.92nS\approx 255.1M\mathrm{\Omega }$	$C\mathbf{}{S}_{n\mathbf{}e\mathbf{}c\mathbf{}k}\mathrm{/}\mathrm{(}{L}_{n\mathbf{}e\mathbf{}c\mathbf{}k}\mathrm{\cdot }{R}_a\mathrm{)}$  ${\displaystyle 50\text{ to }550M\mathrm{\Omega }(275\pm 27M\mathrm{\Omega })}$ (Popovic et al., 2015)