Abstract
A case of metastatic tapioca melanoma of the iris in a 12-year-old girl is reported. The patient had heterochromia, a red painful eye, and was treated for iritis with secondary glaucoma. In the course of 5 months iris lesions with the clinical appearance of tapioca pudding developed, and biopsy disclosed a melanoma. The eye was immediately enucleated, and pathological examination showed a melanoma with predominantly epithelioid-type cells which had infiltrated the angle, the posterior chamber, and the surgical wounds. Conjunctival extension was noted 10 months after enucleation, and regional lymph node metastases were found 4 months later. Previously reported cases are reviewed and compared with the present case.
Full text
PDF
Images in this article
Selected References
These references are in PubMed. This may not be the complete list of references from this article.
- ASHTON N. PRIMARY TUMOURS OF THE IRIS. Br J Ophthalmol. 1964 Dec;48:650–668. doi: 10.1136/bjo.48.12.650. [DOI] [PMC free article] [PubMed] [Google Scholar]
- CLEASBY G. W. Malignant melanoma of the iris. AMA Arch Ophthalmol. 1958 Sep;60(3):403–417. doi: 10.1001/archopht.1958.00940080421009. [DOI] [PubMed] [Google Scholar]
- Jarrett W. H., Goldberg M. F., Schulze R. R. An unusual iris melanoma. Associated with atrophy of iris pigment epithelium, heterochromia, and multicentric tumor foci. Arch Ophthalmol. 1966 Apr;75(4):469–474. doi: 10.1001/archopht.1966.00970050471005. [DOI] [PubMed] [Google Scholar]
- Reese A. B., Mund M. L., Iwamoto T. Tapioca melanoma of the iris. 1. Clinical and light microscopy studies. Am J Ophthalmol. 1972 Nov;74(5):840–850. doi: 10.1016/0002-9394(72)91204-4. [DOI] [PubMed] [Google Scholar]
- Shields M. B., Campbell D. G., Simmons R. J., Hutchinson B. T. Iris nodules in essential iris atrophy. Arch Ophthalmol. 1976 Mar;94(3):406–410. doi: 10.1001/archopht.1976.03910030194004. [DOI] [PubMed] [Google Scholar]
- Wilson R. S., Fraunfelder F. T., Hanna C. Recurrent tapioca melanoma of the iris and ciliary body treated with the argon laser. Am J Ophthalmol. 1976 Aug;82(2):213–217. doi: 10.1016/0002-9394(76)90420-7. [DOI] [PubMed] [Google Scholar]