Skip to main content
The British Journal of Ophthalmology logoLink to The British Journal of Ophthalmology
. 1980 Jul;64(7):483–486. doi: 10.1136/bjo.64.7.483

Clinical trial with 2% sodium cromoglycate (Opticrom) in vernal keratoconjunctivitis.

M El Hennawi
PMCID: PMC1043743  PMID: 6775687

Abstract

An open assessment study was carried out during the summer of 1972 in which 2% sodium cromoglycate eyedrops were evaluated in the treatment of patients with vernal keratoconjunctivitis. A highly significant number of patients found the eyedrops effective, while a marked improvement was recorded in mild and moderate cases; in severe cases or in acute exacerbations additional steroid therapy was recommended. Sodium cromoglycate eyedrops were found to be as effective as Decadron and superior to Antistin-Privine. Furthermore SCG eyedrops could replace or reduce local steroid therapy in vernal keratoconjuntivitis and so avert the possible rise in ocular tension caused by steroids.

Full text

PDF
483

Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. BERNSTEIN H. N., SCHWARTZ B. Effects of long-term systemic steroids on ocular pressure and tonographic values. Arch Ophthalmol. 1962 Dec;68:742–753. doi: 10.1001/archopht.1962.00960030746009. [DOI] [PubMed] [Google Scholar]
  2. Easty D. L., Rice N. S., Jones B. R. Clinical trial of topical disodium cromoglycate in vernal kerato-conjunctivitis. Clin Allergy. 1972 Jun;2(2):99–107. doi: 10.1111/j.1365-2222.1972.tb01274.x. [DOI] [PubMed] [Google Scholar]
  3. Foreman J. C., Garland L. G. Cromoglycate and other antiallergic drugs: a possible mechanism of action. Br Med J. 1976 Apr 3;1(6013):820–821. doi: 10.1136/bmj.1.6013.820. [DOI] [PMC free article] [PubMed] [Google Scholar]
  4. Frankland A. W., Easty D. Vernal kerato-conjunctivitis: an atopic disease. Trans Ophthalmol Soc U K. 1971;91:479–482. [PubMed] [Google Scholar]
  5. Heatley R. V., Calcraft B. J., Rhodes J., Owen E., Evans B. K. Disodium cromoglycate in the treatment of chronic proctitis. Gut. 1975 Jul;16(7):559–563. doi: 10.1136/gut.16.7.559. [DOI] [PMC free article] [PubMed] [Google Scholar]
  6. Jones B. R. Allergic disease of the outer eye. Trans Ophthalmol Soc U K. 1971;91:441–447. [PubMed] [Google Scholar]
  7. Mani V., Lloyd G., Green F. H., Fox H., Turnberg L. A. Treatment of ulcerative colitis with oral disodium cromoglycate. A double-blind controlled trial. Lancet. 1976 Feb 28;1(7957):439–441. doi: 10.1016/s0140-6736(76)91471-9. [DOI] [PubMed] [Google Scholar]
  8. Schär M. Umweltsfaktoren und persönliches Verhalten als Ursache von Erkrankungen der Atmungsorgane. Respiration. 1969;26(Suppl):5–15. [PubMed] [Google Scholar]
  9. Tabbara K. F., Arafat N. T. Cromolyn effects on vernal keratoconjunctivitis in children. Arch Ophthalmol. 1977 Dec;95(12):2184–2186. doi: 10.1001/archopht.1977.04450120090009. [DOI] [PubMed] [Google Scholar]

Articles from The British Journal of Ophthalmology are provided here courtesy of BMJ Publishing Group

RESOURCES