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. 1980 Nov;64(11):818–825. doi: 10.1136/bjo.64.11.818

Experimental occlusion of the central artery of the retina. IV: Retinal tolerance time to acute ischaemia.

S S Hayreh, T A Weingeist
PMCID: PMC1043826  PMID: 7426553

Abstract

Ophthalmoscopic, fluorescein angiographic, electrophysiological, and morphological studies on 63 eyes of rhesus monkeys with acute transient experimental occlusion of the central artery of the retina (OCAR) showed that the retina suffered irreparable damage after ischaemia of 105 minutes but recovered well after ischaemia of 97-98 minutes. The tolerance time of the brain to acute transient ischaemia is many times shorter than that of the retina. The metabolism of ischaemic neurones (in the retina and brain) is discussed with a view to explaining this difference, and also the various factors possibly responsible for the retina's longer tolerance to ischaemia, as compared to the brain.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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