Fig. 2.

RNA-seq analysis reveals coordinated upregulation of canonical EFTFs during optic vesicle development. (A) Heatmap displaying gene expression across the OV time course, for canonical eye-field genes, differentially upregulated (EF-up) genes and genes known to have an important role in early eye development. (B) Clustering of EF-up and EF-down gene trajectories reveals six clusters with three underlying patterns across the time course. At each time point, heatmap and trajectory plots indicate expression averaged across triplicates.