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. 2023 Aug 23;10(8):ENEURO.0227-23.2023. doi: 10.1523/ENEURO.0227-23.2023

Table 1.

Summary of bootstrapped statistical analysis

Variable N
(core/shell)
Difference of mean p-value Confidence interval
Lower (2.5%) Higher (97.5%)
Nuclei volume 39/33 −27.917 0.022 −49.197 −5.654
Nucleoli density 39/33 0.284 0.22 −0.004 0.622
Nucleoli volume 10/10 0.888 0.01 0.282 1.513
Stigmoid body volume 10 0.128 0.725 −0.7676 0.514
Stigmoid body diameter 10 0.092 0.547 −0.429 0.241
Somatic synapses 33/27 −1.990 0.029 −5.909 2.148
Proximal dendrites synapses 83/56 −5.290112 0.0488 −14.488749 4.118613
Soma mRGCs synapses 33/27 −2.79798 9e-04 −4.632997 −1.003367
Soma nonretinal synapses 33/27 1.124579 0.556 −1.437879 4.030471
Proxi dendrites mRGCs synapses 83/56 −9.194258 1e-04 −14.714626 −3.669399
Proxi dendrites nonretinal synapses 83/56 3.424585 0.6242 −2.507282 9.402726
DDCS linear density 5/11 −0.891 0.895 −2.762 0.325
DDCS vesicles 10/8 −217.927 0.160 −459.158 15.78672
Core mRGCs synapses (DDCS+/DDCS−) 25/11 8.674 0.003 2.560 15.802
Shell mRGCs synapses (DDCS+/DDCS−) 27/5 11.536 0.005 5.305 18.467
Core nonretinal synapses (DDCS+/DDCS−) 25/11 13.288 0.003 6.251 20.385
Shell nonretinal synapses (DDCS+/DDCS−) 27/5 14.506 0.003 7.001 23.164
Myelinated axon length 83/54 10.104 0.006 2.397 17.905
mRGCs axon length 50/50 1.469 0.721 −10.725 13.725
Nonretinal axon length 50/50 3.731 0.787 −6.710 14.325
mRGCs bouton linear density 50/50 −1.492 0.153 −4.194 1.243
Nonretina bouton linear density 50/50 1.172 0.360 −1.688 4.596
Bouton volume (mRGC/nonretinal without) 50/50 −0.5451 6e-4 −0.938 −0.200
Bouton volume (nonretinal without/with) 50/50 −0.572 5e-4 −0.996 −0.122
Mitochondria number (mRGC/nonretinal without) 50/50 −0.675 0.026 −1.475 0.075
Mitochondria number (nonretinal without/with) 50/50 −0.925 0.003 −1.775 −0.025
Synapse per bouton (mRGC/nonretinal without) 50/50 −0.2 0.185 −0.525 0.125
Synapse per bouton (nonretinal without/with) 50/50 −0.35 0.031 −0.675 −0.025
Vesicles density (mRGC/nonretinal without) 50/50 281.296 0.018 107.597 468.311
Vesicles density (nonretinal without/with) 50/50 430.199 4.8e-10 314.409 543.212
Mitochondria volume (mRGC/nonretinal without) 71/98 −0.009 0.2292 −0.023 0.004
Mitochondria volume (nonretinal without/with) 98/135 −0.015 3.1e-5 −0.028 −0.002

Bold values indicate significant difference.