Abstract
In a double-blind study of the treatment of vaginal candidiasis, miconazole nitrate gave a cure-rate of 88 per cent. (29 out of 33) compared with 58 per cent. (21 out of 36) using chlordantoin. Although approximately two-thirds of the patients who responded did so to a 10-day course of treatment, the different rates of cure with these preparations at this stage were not statistically significant. However, when a second course of treatment was given to those women who still had proven candidiasis, the overall cure-rate with miconazole was significantly greater than that with chlordantoin.
Full text
PDF

Selected References
These references are in PubMed. This may not be the complete list of references from this article.
- Friedrich E. G., Jr Relief for Herpes vulvitis. Obstet Gynecol. 1973 Jan;41(1):74–77. [PubMed] [Google Scholar]
- HIATT C. W., KAUFMAN E., HELPRIN J. J., BARON S. Inactivation of viruses by the photodynamic action of toluidine blue. J Immunol. 1960 May;84:480–484. [PubMed] [Google Scholar]
- HUTFIELD D. C. EFFECTS OF 5-IODO-2' -DEOXYURIDINE AND PHENYLMERCURIC DINAPHTHYLMETHANE DISULPHONATE ON HERPES GENITALIS. Br J Vener Dis. 1964 Sep;40:210–212. doi: 10.1136/sti.40.3.210. [DOI] [PMC free article] [PubMed] [Google Scholar]
- KAUFMAN H., MARTOLA E. L., DOHLMAN C. Use of 5-iodo-2'-deoxyuridine (IDU) in treatment of herpes simplex keratitis. Arch Ophthalmol. 1962 Aug;68:235–239. doi: 10.1001/archopht.1962.00960030239015. [DOI] [PubMed] [Google Scholar]
- Kaufman R. H., Gardner H. L., Brown D., Wallis C., Rawls W. E., Melnick J. L. Herpes genitalis treated by photodynamic inactivation of virus. Am J Obstet Gynecol. 1973 Dec 15;117(8):1144–1146. doi: 10.1016/0002-9378(73)90768-0. [DOI] [PubMed] [Google Scholar]
- Lefebvre E. B., McNellis E. E. Photoinactivation of herpes simplex. JAMA. 1973 May 14;224(7):1039–1039. doi: 10.1001/jama.224.7.1039b. [DOI] [PubMed] [Google Scholar]
- Moore C., Wallis C., Melnick J. L., Kuns M. D. Photodynamic treatment of herpes keratitis. Infect Immun. 1972 Feb;5(2):169–171. doi: 10.1128/iai.5.2.169-171.1972. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Ng A. B., Reagan J. W., Yen S. S. Hepres genitalis; clinical and cytopathologic experience with 256 patients. Obstet Gynecol. 1970 Oct;36(4):645–651. [PubMed] [Google Scholar]
- Person D. A., Sheridan P. J., Herrmann E. C. Sensitivity of Types 1 and 2 Herpes Simplex Virus to 5-Iodo-2'-Deoxyuridine and 9-beta-d-Arabinofuranosyladenine. Infect Immun. 1970 Dec;2(6):815–820. doi: 10.1128/iai.2.6.815-820.1970. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Proost J. M., Maes-Dockx F. M., Nelis M. O., Van Cutsem J. M. Miconazole in the treatment of mycotic vulvovaginitis. Am J Obstet Gynecol. 1972 Mar;112(5):688–692. doi: 10.1016/0002-9378(72)90796-x. [DOI] [PubMed] [Google Scholar]
- Rawls W. E., Gardner H. L., Flanders R. W., Lowry S. P., Kaufman R. H., Melnick J. L. Genital herpes in two social groups. Am J Obstet Gynecol. 1971 Jul 1;110(5):682–689. doi: 10.1016/0002-9378(71)90254-7. [DOI] [PubMed] [Google Scholar]
- SCHOFIELD C. B. THE TREATMENT OF HERPES PROGENITALIS WITH 5 IODO-2'-DEOXYURIDINE. Br J Dermatol. 1964 Nov;76:465–470. doi: 10.1111/j.1365-2133.1964.tb15486.x. [DOI] [PubMed] [Google Scholar]
- Schneider G. T., Geary W. L. Vaginitis in adolescent girls. Clin Obstet Gynecol. 1971 Dec;14(4):1057–1076. doi: 10.1097/00003081-197112000-00008. [DOI] [PubMed] [Google Scholar]
- WALLIS C., MELNICK J. L. IRREVERSIBLE PHOTOSENSITIZATION OF VIRUSES. Virology. 1964 Aug;23:520–527. doi: 10.1016/0042-6822(64)90236-3. [DOI] [PubMed] [Google Scholar]
- Wallis C., Melnick J. L., Kaufman R. H. Herpes genitalis: management--present and predicted. Clin Obstet Gynecol. 1972 Dec;15(4):939–947. doi: 10.1097/00003081-197212000-00008. [DOI] [PubMed] [Google Scholar]
- YAMAMOTO N. Photodynamic inactivation of bacteriophage and its inhibition. J Bacteriol. 1958 Apr;75(4):443–448. doi: 10.1128/jb.75.4.443-448.1958. [DOI] [PMC free article] [PubMed] [Google Scholar]
