Abstract
Virulent and avirulent gonococcal colonies were studied in the scanning electron microscope. Cells in virulent, in contrast to avirulent, colonies were found to be connected by numerous strands. After longer incubation periods, type 2 colonies segregated out regions of cells virtually lacking these strands. Cells within these areas probably represent avirulent segregants. The microstructure of individual colonies revealed no topographical differences. In certain colonies large smooth spherical cells were seen, probably representing wall-deficient gonococcal variants.
Full text
PDF





Images in this article
Selected References
These references are in PubMed. This may not be the complete list of references from this article.
- Brookes R., Hedén C. G. Dense cultures of Neisseria gonorrhoeae in liquid medium. Appl Microbiol. 1967 Mar;15(2):219–223. doi: 10.1128/am.15.2.219-223.1967. [DOI] [PMC free article] [PubMed] [Google Scholar]
- DIENES L., BANDUR B. M., MADOFF S. DEVELOPMENT OF L-TYPE GROWTH IN NEISSERIA GONORRHOEAE CULTURES. J Bacteriol. 1964 Jun;87:1471–1476. doi: 10.1128/jb.87.6.1471-1476.1964. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Elmros T., Hörstedt P., Winblad B. Scanning electron microscopic study of virulent and avirulent colonies of Neisseria gonorrhoeae. Infect Immun. 1975 Sep;12(3):630–637. doi: 10.1128/iai.12.3.630-637.1975. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Gnarpe H., Wallin J., Forsgren A. Studies in venereal disease. I. Isolation of L-phase organisms of N. gonorrhoeae from patients with gonorrhoea. Br J Vener Dis. 1972 Dec;48(6):496–499. doi: 10.1136/sti.48.6.496. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Hebeler B. H., Young F. E. Autolysis of Neisseria gonorrhoeae. J Bacteriol. 1975 May;122(2):385–392. doi: 10.1128/jb.122.2.385-392.1975. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Jephcott A. E., Reyn A., Birch-Andersen A. Neisseria gonorrhoeae 3. Demonstration of presumed appendages to cells from different colony types. Acta Pathol Microbiol Scand B Microbiol Immunol. 1971;79(3):437–439. doi: 10.1111/j.1699-0463.1971.tb00086.x. [DOI] [PubMed] [Google Scholar]
- Jephcott A. E., Reyn A. Neisseria gonorrhoeae. Colony variation I. Acta Pathol Microbiol Scand B Microbiol Immunol. 1971;79(5):609–614. doi: 10.1111/j.1699-0463.1971.tb00088.x. [DOI] [PubMed] [Google Scholar]
- KELLOGG D. S., Jr, PEACOCK W. L., Jr, DEACON W. E., BROWN L., PIRKLE D. I. NEISSERIA GONORRHOEAE. I. VIRULENCE GENETICALLY LINKED TO CLONAL VARIATION. J Bacteriol. 1963 Jun;85:1274–1279. doi: 10.1128/jb.85.6.1274-1279.1963. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Lawson J. W., Douglas J. T. Induction and reversion of the L-form of Neisseria gonorrhoeae. Can J Microbiol. 1973 Sep;19(9):1145–1151. doi: 10.1139/m73-182. [DOI] [PubMed] [Google Scholar]
- Mayer L. W., Holmes K. K., Falkow S. Characterization of plasmid deoxyribonucleic acid from Neisseria gonorrhoeae. Infect Immun. 1974 Oct;10(4):712–717. doi: 10.1128/iai.10.4.712-717.1974. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Morse S. A., Bartenstein L. Factors affecting autolysis of Neisseria gonorrhoeae. Proc Soc Exp Biol Med. 1974 Apr;145(4):1418–1421. doi: 10.3181/00379727-145-38025. [DOI] [PubMed] [Google Scholar]
- Sparling P. F., Yobs A. R. Colonial morphology of Neisseria gonorrhoeae isolated from males and females. J Bacteriol. 1967 Jan;93(1):513–513. doi: 10.1128/jb.93.1.513-.1967. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Stiffler P. W., Lerner S. A., Bohnhoff M., Morello J. A. Plasmid deoxyribonucleic acid in clinical isolates of Neisseria gonorrhoeae. J Bacteriol. 1975 Jun;122(3):1293–1300. doi: 10.1128/jb.122.3.1293-1300.1975. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Swanson J., Kraus S. J., Gotschlich E. C. Studies on gonococcus infection. I. Pili and zones of adhesion: their relation to gonococcal growth patterns. J Exp Med. 1971 Oct 1;134(4):886–906. doi: 10.1084/jem.134.4.886. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Swanson J., Sparks E., Young D., King G. Studies on Gonococcus infection. X. Pili and leukocyte association factor as mediators of interactions between gonococci and eukaryotic cells in vitro. Infect Immun. 1975 Jun;11(6):1352–1361. doi: 10.1128/iai.11.6.1352-1361.1975. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Wolf-Watz H., Elmros T., Normark S., Bloom G. D. Cell envelope of Neisseria gonorrhoeae: outer membrane and peptidoglycan composition of penicillin-sensitive and-resistant strains. Infect Immun. 1975 Jun;11(6):1332–1341. doi: 10.1128/iai.11.6.1332-1341.1975. [DOI] [PMC free article] [PubMed] [Google Scholar]









