Abstract
46 women with trichomoniasis and gonorrhea were treated with nimorazole (300 mg twice daily for 7 days) and a trichomonal cure rate of 90-2 per cent. was noted. In addition, 53 of 112 patients with trichomoniasis but without gonorrhoea, were treated with metronidazole (200 mg three times a day for 7 days) and 59 with nimorazole (300 mg twice daily for 7 days) in a randomized trial. The cure rates were 96 and 90-5 per cent. respectively. There was no significant difference in the results noted in the two groups. Neither the trichomonal infection itself nor the result of antitrichomonal therapy was affected by antigonococcal therapy (one-day treatment with ampicillin or single-dose therapy with doxycycline). No increase was noted in the frequency of candidiasis after antitrichomonal therapy (in patients without gonorrhoea) or after antigonococcal therapy, but there was substantial variation between consecutive specimens in the prevalence of C. albicans.
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Selected References
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- Bénazet F., Guillaume L. Metronidazole and nitrimidazine. Lancet. 1972 Mar 11;1(7750):597–597. doi: 10.1016/s0140-6736(72)90394-7. [DOI] [PubMed] [Google Scholar]
- CSONKA G. W. LONG-TERM ASPECT OF TREATMENT WITH METRONIDAZOLE (FLAGYL) IN TRICHOMONAL VAGINITIS. Br J Vener Dis. 1963 Dec;39:258–260. doi: 10.1136/sti.39.4.258. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Catterall R. D. Influence of gestogenic contraceptive pills on vaginal candidosis. Br J Vener Dis. 1971 Feb;47(1):45–47. doi: 10.1136/sti.47.1.45. [DOI] [PMC free article] [PubMed] [Google Scholar]
- DIAMOND L. S. The establishment of various trichomonads of animals and man in axenic cultures. J Parasitol. 1957 Aug;43(4):488–490. [PubMed] [Google Scholar]
- Enfors W., Eriksson G. Comparison of oral ampicillin and doxycycline in the treatment of uncomplicated gonorrhoea. Br J Vener Dis. 1975 Apr;51(2):99–103. doi: 10.1136/sti.51.2.99. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Eriksson G., Wanger L. Frequency of N. gonorrhoeae, T. vaginalis, and C. albicans in female venereological patients. A one-year study. Br J Vener Dis. 1975 Jun;51(3):192–197. doi: 10.1136/sti.51.3.192. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Evans B. A., Catterall R. D. Nitrimidazine compared with metronidazole in the treatment of vaginal trichomoniasis. Br Med J. 1971 Oct 16;4(5780):146–147. doi: 10.1136/bmj.4.5780.146. [DOI] [PMC free article] [PubMed] [Google Scholar]
- KANE P. O., McFADZEAN J. A., SQUIRES S. Absorption and excretion of metronidazole. II. Studies on primary failures. Br J Vener Dis. 1961 Dec;37:276–277. doi: 10.1136/sti.37.4.276. [DOI] [PMC free article] [PubMed] [Google Scholar]
- McCann J. S., Mahony J. D., Harris J. R. Comparison of nitrimidazine and metronidazole in the treatment of trichomonal vaginitis. Br J Vener Dis. 1972 Oct;48(5):387–390. doi: 10.1136/sti.48.5.387. [DOI] [PMC free article] [PubMed] [Google Scholar]
- McClean A. N. Nitrimidazine (Naxogin) compared with metronidazole (Flagyl) in the treatment of trichomonal vaginitis. Br J Vener Dis. 1972 Feb;48(1):69–70. doi: 10.1136/sti.48.1.69. [DOI] [PMC free article] [PubMed] [Google Scholar]
- McFadzean J. A., Pugh I. M., Squires S. L., Whelan J. P. Further observations on strain sensitivity of Trichomonas vaginalis to metronidazole. Br J Vener Dis. 1969 Jun;45(2):161–162. doi: 10.1136/sti.45.2.161. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Moffett M., McGill M. I., Schofield C. B., Masterton G. Nitrimidazine in the treatment of trichomoniasis. Br J Vener Dis. 1971 Jun;47(3):173–176. doi: 10.1136/sti.47.3.173. [DOI] [PMC free article] [PubMed] [Google Scholar]
- RODIN P., KING A. J., NICOL C. S., BARROW J. Flagyl in the treatment of trichomoniasis. Br J Vener Dis. 1960 Sep;36:147–151. doi: 10.1136/sti.36.3.147. [DOI] [PMC free article] [PubMed] [Google Scholar]