Abstract
Sera from 600 male homosexual patients were tested for hepatitis B antigen (HBs Ag) and its antibody (HBs Ab). Thirty-one men (5-2%) were positive for HBs Ag. Testing for HBs Ab by immuno-osmoelectrophoresis 33 men (5-5%) were positive. However, sera of 85 patients negative for HBs Ab by routine methods were examined for HBs Ab by radioimmune assay. Thirty (35%) sera were found to be positive. No absolute correlation between the detection of HBs Ag, or previous history of hepatitis, jaundice, or current hepatitis was found. Similarly there was little correlation between presence of HBs Ab and this history. These observations suggest that the male homosexual population represents a pool of individuals within which the hepatitis B virus is readily transmitted, mainly as a subclinical infection although clinical hepatitis does occur in some patients. It is suggested that further work is necessary to determine whether the high antibody rate in male homosexuals is related more to sexual practice than to promiscuity.
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- Fulford K. W., Dane D. S., Catterall R. D., Woof R., Denning J. V. Australia antigen and antibody among patients attending a clinic for sexually transmitted diseases. Lancet. 1973 Jun 30;1(7818):1470–1473. doi: 10.1016/s0140-6736(73)91810-2. [DOI] [PubMed] [Google Scholar]
- Heathcote J., Sherlock S. Spread of acute type-B hepatitis in London. Lancet. 1973 Jun 30;1(7818):1468–1470. doi: 10.1016/s0140-6736(73)91809-6. [DOI] [PubMed] [Google Scholar]
- Hersh T., Melnick J. L., Goyal R. K., Hollinger F. B. Nonparenteral transmission of viral hepatitis type B (Australia antigen-associated serum hepatitis). N Engl J Med. 1971 Dec 9;285(24):1363–1364. doi: 10.1056/NEJM197112092852408. [DOI] [PubMed] [Google Scholar]
- Jeffries D. J., James W. H., Jefferiss F. J., MacLeod K. G., Willcox R. R. Australia (hepatitis-associated) antigen in patients attending a venereal disease clinic. Br Med J. 1973 May 26;2(5864):455–456. doi: 10.1136/bmj.2.5864.455. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Papaevangelou G., Hoofnagle J., Kremastinou J. Transplacental transmission of hepatitis-B virus by symptom-free chronic carrier mothers. Lancet. 1974 Sep 28;2(7883):746–748. doi: 10.1016/s0140-6736(74)90942-8. [DOI] [PubMed] [Google Scholar]
- Reinicke V., Dybkjaer E., Poulsen H., Banke O., Lylloff K., Nordenfelt E. A study of Australia-antigen-positive blood donors and their recipients, with special reference to liver histology. N Engl J Med. 1972 Apr 20;286(16):867–870. doi: 10.1056/NEJM197204202861604. [DOI] [PubMed] [Google Scholar]
- Vahrman J. Spread of acute type-B hepatitis in London. Lancet. 1973 Jul 21;2(7821):157–157. doi: 10.1016/s0140-6736(73)93108-5. [DOI] [PubMed] [Google Scholar]
- Vahrman J. Transmission of hepatitis. Lancet. 1970 Oct 10;2(7676):774–774. doi: 10.1016/s0140-6736(70)90248-5. [DOI] [PubMed] [Google Scholar]