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. 1982 Oct;58(5):321–326. doi: 10.1136/sti.58.5.321

Anaerobes in men with urethritis

E A Fontaine 1, D Taylor-Robinson 1, N F Hanna 1, E D Coufalik 1
PMCID: PMC1046085  PMID: 7127057

Abstract

Sixty-four men with non-gonococcal urethritis (NGU), seven with gonococcal urethritis (GU), and 30 who had no symptoms or signs of urethritis were studied. Chlamydia trachomatis was isolated from urethral specimens taken from 22% of the men with NGU, and 18% with GU, but not from those who did not have urethritis even though 20 (67%) of them had a history of NGU, GU, or both. The chlamydial isolation rate for men having NGU for the first time was 30%. Ureaplasma urealyticum was isolated from 42% of the men with NGU, 43% of men with GU, and 27% of those without urethritis.

In addition to aerobes anaerobes were isolated frequently from men whether or not they had urethritis, the most common being anaerobic Corynebacteria, peptococci, and micro-organisms of the Bacteroides-Fusobacteria group. There was no appreciable difference in the overall isolation of anaerobes from men with NGU (89%) or from those without disease (80%). The rate of isolation of a Gram-negative anaerobic bacillus from men with NGU (50%) was, however, strikingly different to that from men with GU (14%) or from those without disease (13%). Furthermore, this bacillus was recovered from 28 (56%) of 50 men with NGU who were considered chlamydia-negative and from 19 (61%) of 31 men who were both chlamydia-negative and ureaplasma-negative. The effect of antibiotic treatment was evaluated in a few patients only, so that although those from whom the Gram-negative bacillus was eliminated by tetracycline recovered clinically there is a need for a prospective therapeutic trial to evaluate further the importance of the bacillus.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. Bowie W. R., Pollock H. M., Forsyth P. S., Floyd J. F., Alexander E. R., Wang S. P., Holmes K. K. Bacteriology of the urethra in normal men and men with nongonococcal urethritis. J Clin Microbiol. 1977 Nov;6(5):482–488. doi: 10.1128/jcm.6.5.482-488.1977. [DOI] [PMC free article] [PubMed] [Google Scholar]
  2. Coufalik E. D., Taylor-Robinson D., Csonka G. W. Treatment of nongonococcal urethritis with rifampicin as a means of defining the role of Ureaplasma urealyticum. Br J Vener Dis. 1979 Feb;55(1):36–43. doi: 10.1136/sti.55.1.36. [DOI] [PMC free article] [PubMed] [Google Scholar]
  3. Fontaine E. A., Taylor-Robinson D., Borriello S. P., Hanna N. F., Honour P. Impact of neonatal intensive care. Lancet. 1982 Jan 30;1(8266):281–281. doi: 10.1016/s0140-6736(82)91004-2. [DOI] [PubMed] [Google Scholar]
  4. Fontaine E. A., Taylor-Robinson D. Evaluation of liquid transport media for the isolation of anaerobic bacteria: relevance to genital tract specimens. J Infect. 1981 Dec;3(4):360–369. doi: 10.1016/s0163-4453(81)91977-0. [DOI] [PubMed] [Google Scholar]
  5. Furness G., Evangelista A. T., Kaminski Z. Corynebacterium genitalium (nonspecific urethritis corynebacteria). Biologic reactions differentiating commensals of the urogenital tract from the pathogens responsible for urethritis. Invest Urol. 1977 Jul;15(1):23–27. [PubMed] [Google Scholar]
  6. Furness G., Kamat M. H., Kaminski Z., Seebode J. J. Isolation of corynebacteria from non-specific urethritis. J Urol. 1971 Oct;106(4):557–561. doi: 10.1016/s0022-5347(17)61340-5. [DOI] [PubMed] [Google Scholar]
  7. Hafiz S., McEntegart M. G., Morton R. S., Waitkins S. A. Clostridium defficiel in the urogenital tract of males and females. Lancet. 1975 Feb 22;1(7904):420–421. doi: 10.1016/s0140-6736(75)91489-0. [DOI] [PubMed] [Google Scholar]
  8. Hallén A., Rydén A. C., Schwan A., Wallin J. The possible role of anaerobic bacteria in the aetiology of non-gonococcal urethritis in men. Br J Vener Dis. 1977 Dec;53(6):368–371. doi: 10.1136/sti.53.6.368. [DOI] [PMC free article] [PubMed] [Google Scholar]
  9. Justesen T., Nielsen M. L., Hattel T. Anaerobic infections in chronic prostatitis and chronic urethritis. Med Microbiol Immunol. 1973 Mar 8;158(3):237–248. doi: 10.1007/BF02120559. [DOI] [PubMed] [Google Scholar]
  10. Malone B. H., Schreiber M., Schneider N. J., Holdeman L. V. Obligately anaerobic strains of Corynebacterium vaginale (Haemophilus vaginalis). J Clin Microbiol. 1975 Sep;2(3):272–275. doi: 10.1128/jcm.2.3.272-275.1975. [DOI] [PMC free article] [PubMed] [Google Scholar]
  11. Munday P. E., Thomas B. J., Johnson A. P., Altman D. G., Robinson D. T. Clinical and microbiological study of non-gonococcal urethritis with particular reference to non-chlamydial disease. Br J Vener Dis. 1981 Oct;57(5):327–333. doi: 10.1136/sti.57.5.327. [DOI] [PMC free article] [PubMed] [Google Scholar]
  12. Prentice M. J., Taylor-Robinson D., Csonka G. W. Non-specific urethritis. A placebo-controlled trial of minocycline in conjunction with laboratory investigations. Br J Vener Dis. 1976 Aug;52(4):269–275. doi: 10.1136/sti.52.4.269. [DOI] [PMC free article] [PubMed] [Google Scholar]
  13. Segura J. W., Kelalis P. P., Martin W. J., Smith L. H. Anaerobic bacteria in the urinary tract. Mayo Clin Proc. 1972 Jan;47(1):30–33. [PubMed] [Google Scholar]
  14. Taylor-Robinson D., Evans R. T., Coufalik E. D., Prentice M. J., Munday P. E., Csonka G. W., Oates J. K. Ureaplasma urealyticum and Mycoplasma hominis in chlamydial and non-chlamydial nongonococcal urethritis. Br J Vener Dis. 1979 Feb;55(1):30–35. doi: 10.1136/sti.55.1.30. [DOI] [PMC free article] [PubMed] [Google Scholar]
  15. Willcox R. R. 'Triple tetracycline' in the treatment of non-gonococcal urethritis in males. Br J Vener Dis. 1972 Apr;48(2):137–140. doi: 10.1136/sti.48.2.137. [DOI] [PMC free article] [PubMed] [Google Scholar]

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