Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2023 Aug 6;13(13):4430–4448. doi: 10.7150/thno.85369

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© The author(s)

This is an open access article distributed under the terms of the Creative Commons Attribution License (https://creativecommons.org/licenses/by/4.0/). See http://ivyspring.com/terms for full terms and conditions.

PMC Copyright notice

Secretory proteins favoring hepatocellular malignant transformation in senescent HSCs. (A) Fold change of 14 secretory proteins in association with HCC development in F30 compared to controls (p < 0.05). (B) Fold change of 13 secretory proteins involved in cell proliferation and tumor invasion in F30 compared to controls (p < 0.05). (C) Fold change of 11 secretory proteins involved in epithelial-mesenchymal transition (EMT) in F30 compared to controls (p < 0.05). (D) Fold change of 4 secretory proteins involved in DNA damage, cell cycle and tumor immune escape in F30 compared to controls (p < 0.05). (E) Fold change of 7 secretory proteins contributing to HCC inhibition in F30 compared to controls (p < 0.05). (F) Protein-protein interaction network (PPI network) of differential secretory proteins. Size and color shade of the cycle represent the number of interacting proteins. Proteins are sorted according to quantity in clockwise.