Table 6. Multivariate Cox regression model with associated hazard ratios.
p values have been rounded to two decimal places. PS: performance status, MGMT: O(6)-methylguanine-DNA methyltransferase, IDH: isocitrate dehydrogenase.
| Variable | Mortality (15 months) | |
| Hazard ratio (HR) and 95% confidence intervals (CIs) | p value | |
| Age | 1.02 (1.01, 1.04) | 0.01 |
| Sex | 0.73 (0.50, 1.07) | 0.10 |
| Radiotherapy | 0.42 (0.27, 0.66) | < 0.01 |
| Chemotherapy | 0.60 (0.38, 0.92) | 0.02 |
| Treatment group | 0.88 (0.55, 1.39) | 0.58 |
| MGMT methylation | 0.52 (0.35, 0.78) | < 0.01 |
| IDH mutation | 0.90 (0.37, 2.7) | 0.81 |
| Anatomical location | 2.09 (1.39, 3.13) | < 0.01 |
| Pre-operative PS | 1.00 (0.67, 1.51) | 0.98 |
| Change in PS | 1.16 (0.78, 1.73) | 0.47 |
| New deficit | 1.02 (0.61, 1.69) | 0.94 |
| > 90% resection | 0.49 (0.33, 0.71) | < 0.01 |