Abstract
Of 104 male and nine female patients with uncomplicated acute gonorrhoea who were treated with spectinomycin (males 2 g., females 4 g.), two patients (one male and one female) were considered to be treatment failures. No conclusions can be drawn from the small numbers of female patients investigated. Of the 104 male patients, 93 were followed for 2 weeks or more, giving a failure rate of 1-1 per cent. The drug was well tolerated. Sensitivity tests were carried out on 44 strains of N. gonorrhoeae; 42 strains were sensitive to 2-5 mug./ml. spectinomycin and all strains were sensitive to 5 mug./ml.
Full text
PDF
Selected References
These references are in PubMed. This may not be the complete list of references from this article.
- Gray R. C., Phillips I., Nicol C. S. Treatment of gonorrhoea with three different antibiotic regimes: doxycycline 300 mg., procaine penicillin plus benzyl penicillin 2.4 m.u., benzyl penicillin 5 m.u. plus probenecid. Br J Vener Dis. 1970 Oct;46(5):401–403. doi: 10.1136/sti.46.5.401. [DOI] [PMC free article] [PubMed] [Google Scholar]
- LAIRD S. M., TAYLOR G. Treatment of gonorrhoea with actinospectacin. Br J Vener Dis. 1962 Jun;38:60–63. doi: 10.1136/sti.38.2.60. [DOI] [PMC free article] [PubMed] [Google Scholar]
- MASON D. J., DIETZ A., SMITH R. M. Actinospectacin, a new antibiotic. I. Discovery and biological properties. Antibiot Chemother (Northfield) 1961 Feb;11:118–122. [PubMed] [Google Scholar]
- Thin R. N. Treatment of gonorrhoea in Singapore using penicillin plus probenecid. Br J Vener Dis. 1973 Apr;49(2):216–218. doi: 10.1136/sti.49.2.216. [DOI] [PMC free article] [PubMed] [Google Scholar]