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. 2023 Jul 25;14(4):e01388-23. doi: 10.1128/mbio.01388-23

Fig 4.

Fig 4

POWV N224Q mutation attenuates neurovirulence in C57BL/6 mice. (A) Body weight analysis and (B) Kaplan-Meier survival curves (LI9 vs recLI9-N224Q, P = 0.0442) of pups of C57BL/6 mice (N = WT:5; N224Q:5; Cont:3) intracranially inoculated with 2 × 102 FFU of WT LI9, recLI9-N224Q, or buffer only. (C) Body weight analysis and (D) Kaplan-Meier survival curves (LI9 vs N224Q, P = 0.3310, not significant) for C57BL/6 mice (male, N = WT:8; N224Q:10; Cont:4) footpad inoculated with 2 × 103 FFU of WT LI9, recLI9-N224Q, or a buffer-only control.