Table 2.

Drug-likeness properties of natural polymers and native ligand.

Code	Medicinal Chemistry
	QED	NPscore	Lipinski Rule	Pfizer Rule	GSK Rule	Golden Triangle	Chelator Rule
NL	0.189	−0.942	Rejected	Accepted	Rejected	Rejected	0
Agarose	0.119	1.451	Rejected	Accepted	Rejected	Rejected	0
Alginate	0.242	1.075	Rejected	Accepted	Rejected	Accepted	0
Carrageenan	0.718	−0.778	Accepted	Accepted	Accepted	Accepted	0
Chitosan	0.038	0.384	Rejected	Accepted	Rejected	Rejected	0
Cyclodextrin	0.113	0.65	Rejected	Accepted	Rejected	Rejected	0
Dextran	0.125	1.697	Rejected	Accepted	Rejected	Rejected	0
Hyaluronic acid	0.087	1.107	Rejected	Accepted	Rejected	Rejected	0
Polysialic acid	0.268	1.575	Accepted	Accepted	Accepted	Accepted	0