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. 2023 Sep 5;10(25):2370169. doi: 10.1002/advs.202370169

Yin Yang 1‐Induced Long Noncoding RNA DUXAP9 Drives the Progression of Oral Squamous Cell Carcinoma by Blocking CDK1‐Mediated EZH2 Degradation (Adv. Sci. 25/2023)

Wenkai Zhou, Yisheng Feng, Chengzhong Lin, Chi Kuan CHAO, Ziqi He, Shiyao Zhao, Jieyuan Xue, Xu‐Yun Zhao, Wei Cao
PMCID: PMC10477866

Abstract

Yin Yang 1‐Induced Long Noncoding RNA DUXAP9

A nuclear‐localized lncRNA DUXAP9 blocking CDK1‐mediated EZH2 phosphorylation and inhibiting EZH2 translocation from the nucleus to the cytoplasm, and thereby averting EZH2 degradation, suggesting that DUXAP9 may be a potential target for OSCC therapy. More details can be found in article number 2207549 by Xu‐Yun Zhao, Wei Cao, and co‐workers.

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