Corrigendum: Different pharmacokinetics of tramadol, O-demethyltramadol and N-demethyltramadol in postoperative surgical patients from those observed in medical patients

In the published article, there was an error in Figure 1 as published. The Figures 1B, C were incorrect and appeared inverted in the figure caption.

FIGURE 1.

Concentrations of tramadol (A), N-demethyltramadol (B), and O-demethyltramadol (C) in the first 24 postoperative hours. Concentrations were measured 1, 2, 4 h after the first dose of 100 mg tramadol iv, and just before the second (time point 6 h), third (time point 12 h), and fifth (time point 24 h) doses of tramadol. PM, poor metabolizer; IM, intermediate metabolizer; EM, extensive metabolizer; UM, ultrafast metabolizers; Dot, tramadol 100 mg IV injections; * statistically significant differences (Mann-Whitney U test) between PM and EM/IM (B), and EM and IM/PM (C).

The corrected Figure 1 and its caption appear below.

The authors apologize for this error and state that this does not change the scientific conclusions of the article in any way. The original article has been updated.

Publisher’s note

All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article, or claim that may be made by its manufacturer, is not guaranteed or endorsed by the publisher.