Individualized dosing guidelines for PEGasparaginase and factors influencing the clearance: a population pharmacokinetic model

With reference to our paper published in the May issue 2021 of Haematologica,¹ we would like to draw your attention to Table 5 which contains two typing errors. In fact, in the column “Target trough levels: 100-250 IU/L”, the second “Week level” range should be 100-150 IU/L instead of 100-250 IU/L, while in the column “Target trough levels: 250-400 IU/L” the third “Week level” range should be 300-350 IU/L instead of 300-250 IU/L, as shown in the corrected Table 5 below.

Corrected Table 5.

Dosing guideline, dose adjustments.