Patient Characteristics [Dose-Escalation Phase Ib Part] | |
---|---|
Number of patients, male | 4 |
Number of patients, female | 6 |
Stage | Stage IV (100%) |
Age: median (range) | 62 (48-67) years |
Number of prior systemic therapies: median (range) | 2.5 (1-4) |
Performance status: ECOG | 0: 2 1: 8 2: 0 3: 0 4: 0 |
Cancer types or histologic subtypes | Stomach cancer (adenocarcinoma): 5 [PTEN (−) by IHC, n = 2; HER2 (+), n = 2] Colorectal cancer (adenocarcinoma): 5 [PTEN (−) by IHC, n = 1] |