Skip to main content
Journal of Medical Genetics logoLink to Journal of Medical Genetics
. 1981 Dec;18(6):424–427. doi: 10.1136/jmg.18.6.424

Are congenital vertebral anomalies and spina bifida cystica aetiologically related?

R G Lendon, R Wynne-Davies, M Lendon
PMCID: PMC1048786  PMID: 7038115

Abstract

Radiological records of 104 patients with multiple vertebral anomalies without apparent spina bifida and 112 infants with spina bifida cystica were surveyed and the incidences of hemivertebrae and of rib, vertebral body, and vertebral arch fusions were recorded. The distributions of these four anomalies along the vertebral axis were found not to be statistically different between the two age groups. This is additional evidence to support the hypothesis that multiple vertebral anomalies and anencephaly-spina bifida cystica are aetiologically related.

Full text

PDF
424

Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. McLennan J. E. Rib anomalies in myelodysplasia. An approach to embryologic inference. Biol Neonate. 1976;29(3-4):129–141. doi: 10.1159/000240857. [DOI] [PubMed] [Google Scholar]
  2. Naik D. R., Lendon R. G., Barson A. J. A radiological study of vertebral and rib malformations in children with myelomeningocele. Clin Radiol. 1978 Jul;29(4):427–430. doi: 10.1016/s0009-9260(78)80105-6. [DOI] [PubMed] [Google Scholar]
  3. SHANDS A. R., Jr, BUNDENS W. D. Congenital deformities of the spine; an analysis of the roentgenograms of 700 children. Bull Hosp Joint Dis. 1956 Oct;17(2):110–133. [PubMed] [Google Scholar]
  4. Wynne-Davies R. Congenital vertebral anomalies: aetiology and relationship to spina bifida cystica. J Med Genet. 1975 Sep;12(3):280–288. doi: 10.1136/jmg.12.3.280. [DOI] [PMC free article] [PubMed] [Google Scholar]

Articles from Journal of Medical Genetics are provided here courtesy of BMJ Publishing Group

RESOURCES